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A High-Throughput Platform for Culture and 3D Imaging of Organoids
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Open-Source 3-D Platform for Low-Cost Scientific Instrument Ecosystem.

C Zhang1, B Wijnen1, J M Pearce2

  • 1Department of Materials Science and Engineering, Michigan Technological University, Houghton, MI, USA.

Journal of Laboratory Automation
|January 15, 2016
PubMed
Summary

Open-source 3-D printing technology has been adapted into a versatile scientific platform. This innovation enables low-cost, customized laboratory equipment for diverse research applications, reducing costs globally.

Keywords:
3-D platform3-D printingfluid handlinglaboratory equipmentopen-source hardware

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Area of Science:

  • Engineering
  • Biotechnology
  • Materials Science

Background:

  • Open-source software and hardware offer accessible solutions for scientific research equipment.
  • Open-source 3-D printers are valuable for creating custom scientific tools.

Purpose of the Study:

  • To expand the capabilities of open-source 3-D printers into a flexible scientific platform.
  • To demonstrate a low-cost, automated 3-D motion control system for scientific applications.

Main Methods:

  • Development of an automated low-cost 3-D motion control platform.
  • Integration of 3-D printing for scientific hardware fabrication.
  • Implementation of laboratory automation for stirring, measuring, probing, fluid handling, shaking, and mixing.

Main Results:

  • The platform successfully performs 3-D printing of scientific hardware.
  • Automated laboratory functions including stirring, measuring, and fluid handling were achieved.
  • The system demonstrated capabilities in shaking and mixing for research.

Conclusions:

  • The open-source 3-D platform significantly reduces research costs.
  • This adaptable system facilitates the creation of custom scientific instruments.
  • Digital sharing and replication of designs can further lower global research and education expenses.