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Formation of endothelin by cultured airway epithelial cells
P N Black1, M A Ghatei, K Takahashi
1Department of Clinical Pharmacology, Royal Postgraduate Medical School, London, England.
FEBS Letters
|September 11, 1989
Abstract:
Immunoreactivity to endothelin was detected in conditioned culture medium from both canine and porcine tracheal epithelial cells. Gel permeation chromatography and fast protein liquid chromatography were used to confirm the identity of the endothelin. The two peaks demonstrated on fast protein liquid chromatography co-eluted with endothelin 1 and endothelin 3 respectively.