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Related Experiment Video

Updated: Mar 27, 2026

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans

Published on: August 28, 2018

Interventional Options for Coronary Artery Calcification.

Matthew I Tomey¹, Samin K Sharma²

¹Icahn School of Medicine at Mount Sinai, Cardiovascular Institute, One Gustave L. Levy Place, Box 1030, New York, NY, 10029, USA.

Current Cardiology Reports

|January 16, 2016

Summary

Severe coronary artery calcification hinders percutaneous coronary intervention. Advances in atheroablation now enable successful treatment of calcified lesions with improved safety.

Keywords:

Calcification Complex lesions Coronary artery disease Orbital atherectomy Percutaneous coronary intervention Rotational atherectomy

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Area of Science:

Cardiovascular Medicine
Interventional Cardiology
Atherosclerosis Research

Background:

Coronary artery calcification (CAC) is a key component of atherosclerosis.
Moderate to severe CAC poses significant challenges during percutaneous coronary intervention (PCI).
Historically, PCI for calcified lesions had lower success rates and higher complication risks.

Purpose of the Study:

To provide an updated overview of CAC pathobiology.
To review current interventional management strategies for calcified coronary lesions.

Main Methods:

Focused review of existing literature on CAC and PCI techniques.
Discussion of atheroablation technologies such as rotational and orbital atherectomy.

Main Results:

Atheroablation technologies have significantly improved PCI success rates for calcified lesions.
Current techniques offer a favorable safety profile for managing complex calcified coronary lesions.

Conclusions:

PCI for calcified coronary lesions is now feasible with high success and safety.
Advances in atheroablation have transformed the management of complex coronary artery disease.