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Ionic liquid supported organotin reagents to prepare molecular imaging and therapy agents
Holisoa Rajerison1, Djibril Faye2, Aurélia Roumesy1
1Université de Nantes, CRCNA, UMR 892 INSERM-6299 CNRS, 8 Quai Moncousu, 44000 Nantes, France. holisoa.rajerison@univ-nantes.fr jfgestin@nantes.inserm.fr.
Organic & Biomolecular Chemistry
|January 20, 2016
Abstract:
Efficiency of ionic liquid supported organotin reagents in halodemetalation reaction has been investigated. High radiochemical yields of astatinated and iodinated compounds have been obtained using simple work-up procedure. This methodology represents a straightforward approach for the preparation of molecular imaging and therapy agents in nuclear medicine.
