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Next-generation sequencing as an approach to dairy starter selection
Philip Kelleher1, James Murphy1, Jennifer Mahony1
1School of Microbiology, University College Cork, Cork, Ireland.
Dairy Science & Technology
|January 23, 2016
Summary
Selecting novel dairy starter cultures requires advanced genomic analysis. Whole genome sequencing aids in identifying robust lactococcal and streptococcal strains, overcoming phage sensitivity for improved fermented dairy products.
Area of Science:
- Dairy microbiology
- Genomics
- Food science
Background:
- Lactococcal and streptococcal starter strains are essential for fermented dairy production.
- Phage sensitivity and the need for novel products drive the demand for improved starter culture selection technologies.
Approach:
- This review examines methodologies for assessing the technological potential of dairy starter strains.
- It highlights advancements in dairy starter genomics, particularly leveraging whole genome sequencing.
Key Points:
- Whole genome sequencing, enabled by next-generation sequencing, offers a powerful approach for strain identification and selection.
- Gene-trait matching using genomic data facilitates the rational design of starter culture blends.
- Genomic insights are crucial for overcoming challenges like phage sensitivity in starter cultures.
Conclusions:
- Genomic approaches, especially whole genome sequencing, are revolutionizing the selection of starter cultures for the dairy industry.
- These technologies enable the development of improved starter blends with enhanced traits for novel fermented dairy products.
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