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Updated: Mar 26, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
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Racial and Ethnic Differences in Prenatal Life Stress and Postpartum Depression Symptoms

Cindy H Liu1, Rebecca Giallo2, Stacey N Doan3

  • 1Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA.

Archives of Psychiatric Nursing
|January 26, 2016
PubMed

This study determined the risk of core depression symptoms based on life stress domains during pregnancy and whether stressors varied by race/ethnicity. The sample consisted of 2,344 White, African American, Hispanic, and Asian/Pacific Islander (API) Massachusetts women who recently gave birth. African Americans and Hispanics who endorsed high relational and high financial stress were more likely to report high depressed mood and loss of interest; high physical stress was associated with high depressed mood among API. Screening based on life stress domains may be informative in determining risk for core depression symptoms during the postpartum period especially for minority groups.

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