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Updated: Mar 26, 2026

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Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses
Published on: June 13, 2018
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Access-Related Infections Involving the Buttonhole Technique
Shigeki Toma1, Takahiro Shinzato, Kunihiro Hayakawa
1Toma Clinic, Okinawa, Japan.
Blood Purification
|January 29, 2016
Summary
Staphylococcus aureus can infect buttonhole (BH) dialysis tracks. Prevention involves decolonization, preventing bacterial invasion, and controlling bacterial growth to maintain patient safety.
Area of Science:
- Nephrology
- Infectious Diseases
- Medical Devices
Background:
- Buttonhole (BH) method for vascular access in hemodialysis patients.
- Risk of Staphylococcus aureus (S. aureus) infections associated with BH cannulation.
Purpose of the Study:
- To elucidate the mechanism of S. aureus infections in BH dialysis access.
- To develop evidence-based preventive strategies against these infections.
Main Methods:
- Analysis of S. aureus colonization and infection development in BH tracks.
- Logical construction of a multi-faceted prevention strategy based on identified mechanisms.
Main Results:
- S. aureus can colonize BH tracks, leading to infections when host resistance is compromised.
- A three-pronged approach is proposed for infection prevention.
Conclusions:
- Decolonization of S. aureus carriers using mupirocin ointment.
- Preventing bacterial invasion via complete scab removal.
- Controlling bacterial growth with diluted povidone-iodine disinfection prior to cannulation.
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