Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Neural Circuits01:25

Neural Circuits

3.2K
Neural circuits and neuronal pools are two of the main structures found in the nervous system. Neural circuits are networks of neurons that work together to carry out a specific task or process. They consist of interconnected neurons and glial cells, which provide structural and metabolic support.
Neuronal pools are collections of nerve cells with similar functions and interact through chemical and electrical signals. These pools include both interneurons (the central neural circuit nodes that...
3.2K
Rapidly Varying Flow01:24

Rapidly Varying Flow

629
Rapidly varying flow (RVF) in open channels is characterized by abrupt changes in flow depth over a short distance, with the rate of depth change relative to distance often approaching unity. These flows are inherently complex due to their transient and multi-dimensional nature, making exact analysis difficult. However, approximate solutions using simplified models provide valuable insights into their behavior.Key Features of Rapidly Varying FlowRVF is commonly observed in scenarios involving...
629
Neuronal Communication01:28

Neuronal Communication

4.7K
Neurons, the fundamental units of the brain and nervous system, communicate through complex electrochemical signals that underpin all cognitive and bodily functions. This communication is primarily facilitated by a process involving the generation and propagation of an action potential along the axon of the neuron. When the internal electrical charge of a neuron surpasses a certain threshold, an action potential is triggered. This rapid change in voltage travels swiftly along the axon to the...
4.7K
Flow Table Test01:12

Flow Table Test

933
The flow table test is an established method used to assess the workability of concrete, particularly useful for evaluating highly flowable concrete mixes. This test employs an apparatus that consists of a wooden board topped with a steel plate, collectively weighing 35 pounds. The board is connected to a base via a hinge and measures 27.6 inches on each side.
Concrete is placed within a truncated cone mold that is 8 inches high with an 8-inch base diameter and a 5-inch top diameter. The...
933
Propagation of Action Potentials01:23

Propagation of Action Potentials

13.5K
The propagation of an action potential refers to the process by which a nerve impulse, or "action potential," travels along a neuron.
Neurons (nerve cells) have a resting membrane potential, with a slightly negative charge inside compared to outside. This is maintained by ion channels, such as sodium (Na+) and potassium (K+) channels, which control the flow of ions. When a stimulus, like a touch or a signal from another neuron, triggers the neuron, sodium channels open, allowing sodium ions to...
13.5K
Gradually Varying Flow01:29

Gradually Varying Flow

524
Gradually varying flow (GVF) in open channels describes situations where water depth changes slowly along the channel due to factors like non-uniform bed slope, channel shape variations, or obstructions. This flow type occurs when the depth adjusts gradually to balance gravitational forces, shear forces, and energy requirements, resulting in a low rate of depth change.Characteristics of Gradually Varying FlowGVF is commonly observed in natural streams, rivers, and canals, where flow depth...
524

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A novel liquid-liquid cfDNA extraction method for targeted sequencing with colorectal cancer patient samples: a pilot study.

Frontiers in oncology·2026
Same author

Ultra-wide-field, deep, adaptive two-photon microscopy for multi-scale neuronal imaging.

Light, science & applications·2026
Same author

Synergy mediates long-range correlations in the visual cortex near criticality.

Frontiers in computational neuroscience·2026
Same author

Astrocytes and neurons exhibit partially shared but distinct composite receptive fields for natural stimuli.

Journal of neurophysiology·2026
Same author

Synergy mediates Long-Range Correlations in the Visual Cortex Near Criticality.

bioRxiv : the preprint server for biology·2025
Same author

Hierarchical Bayesian modeling of multiregion brain cell count data.

eLife·2025
Same journal

Synaptic micromechanics and brain softening as a mechanobiological hypothesis for Alzheimer's disease.

Frontiers in neuroscience·2026
Same journal

The relationship between healthy sleep patterns and the risk of scoliosis: a large prospective cohort study.

Frontiers in neuroscience·2026
Same journal

Dynamic functional reorganization in post-stroke aphasia: a state-of-the-art fMRI review from disease evolution to intervention.

Frontiers in neuroscience·2026
Same journal

Correction: Case Report: A possible novel adult-onset, progressive MAO-A hypofunction.

Frontiers in neuroscience·2026
Same journal

Respiratory modulation of neurophysiology and symptoms in athletes with sports-related concussion: a randomized crossover trial.

Frontiers in neuroscience·2026
Same journal

Impact of C-reactive protein-triglyceride-glucose and systemic immune-inflammation indices on obstructive sleep apnea in older adults with depression.

Frontiers in neuroscience·2026
See all related articles

Related Experiment Video

Updated: Mar 26, 2026

Using Neuron Spiking Activity to Trigger Closed-Loop Stimuli in Neurophysiological Experiments
05:19

Using Neuron Spiking Activity to Trigger Closed-Loop Stimuli in Neurophysiological Experiments

Published on: November 12, 2019

7.7K

NeuroFlow: A General Purpose Spiking Neural Network Simulation Platform using Customizable Processors.

Kit Cheung1, Simon R Schultz2, Wayne Luk3

  • 1Custom Computing Research Group, Department of Computing, Imperial College LondonLondon, UK; Centre for Neurotechnology, Department of Bioengineering, Imperial College LondonLondon, UK.

Frontiers in Neuroscience
|February 3, 2016
PubMed
Summary
This summary is machine-generated.

NeuroFlow is a flexible spiking neural network simulation platform using Field-Programmable Gate Arrays (FPGAs). It offers significant speedups for large-scale neural network simulations compared to traditional processors.

Keywords:
FPGAPyNNSTDPhardware acceleratorlarge-scale neural simulationneuromorphicspiking neural network

More Related Videos

Closed-loop Neuro-robotic Experiments to Test Computational Properties of Neuronal Networks
11:18

Closed-loop Neuro-robotic Experiments to Test Computational Properties of Neuronal Networks

Published on: March 2, 2015

11.0K
Interfacing 3D Engineered Neuronal Cultures to Micro-Electrode Arrays: An Innovative In Vitro Experimental Model
09:47

Interfacing 3D Engineered Neuronal Cultures to Micro-Electrode Arrays: An Innovative In Vitro Experimental Model

Published on: October 18, 2015

10.5K

Related Experiment Videos

Last Updated: Mar 26, 2026

Using Neuron Spiking Activity to Trigger Closed-Loop Stimuli in Neurophysiological Experiments
05:19

Using Neuron Spiking Activity to Trigger Closed-Loop Stimuli in Neurophysiological Experiments

Published on: November 12, 2019

7.7K
Closed-loop Neuro-robotic Experiments to Test Computational Properties of Neuronal Networks
11:18

Closed-loop Neuro-robotic Experiments to Test Computational Properties of Neuronal Networks

Published on: March 2, 2015

11.0K
Interfacing 3D Engineered Neuronal Cultures to Micro-Electrode Arrays: An Innovative In Vitro Experimental Model
09:47

Interfacing 3D Engineered Neuronal Cultures to Micro-Electrode Arrays: An Innovative In Vitro Experimental Model

Published on: October 18, 2015

10.5K

Area of Science:

  • Computational Neuroscience
  • High-Performance Computing
  • Neuromorphic Engineering

Background:

  • Spiking neural network (SNN) simulations are crucial for understanding brain function but computationally demanding.
  • Existing hardware platforms like multi-core processors and ASICs have limitations in flexibility and performance for SNNs.
  • Customizable hardware offers potential for optimized SNN simulation performance.

Purpose of the Study:

  • To introduce NeuroFlow, a novel, scalable SNN simulation platform.
  • To demonstrate NeuroFlow's reconfigurable architecture for optimized performance.
  • To evaluate NeuroFlow's simulation capabilities and speedup over conventional hardware.

Main Methods:

  • NeuroFlow utilizes Field-Programmable Gate Arrays (FPGAs) for its customizable processor architecture.
  • The platform supports PyNN for configuring the processor and includes common neuronal models (e.g., integrate-and-fire, Izhikevich) and STDP learning.
  • Performance was evaluated on a 6-FPGA system simulating large neural networks.

Main Results:

  • A 6-FPGA system can simulate up to ~600,000 neurons, achieving real-time performance for 400,000 neurons.
  • NeuroFlow on a single FPGA offers up to 33.6x speedup over an 8-core processor and 2.83x over GPU platforms.
  • The reconfigurable architecture allows for tailored performance optimization.

Conclusions:

  • NeuroFlow provides a highly flexible and high-throughput platform for large-scale SNN simulations.
  • Its FPGA-based architecture offers significant performance advantages over traditional computing systems.
  • NeuroFlow represents a viable environment for advancing computational neuroscience research through efficient simulation.