Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Urinary Tract Infection I: Introduction01:26

Urinary Tract Infection I: Introduction

1.1K
Urinary tract infections (UTIs) impact various parts of the urinary system, including the kidneys, ureters, bladder, and urethra. These infections are generally bacterial, with Escherichia coli being the most common causative agent, often originating from the gastrointestinal tract. However, other bacteria, such as Staphylococcus saprophyticus, Klebsiella pneumoniae, and Proteus mirabilis, are also known to cause UTIs. The type, location, and underlying complexity of the UTI guide both...
1.1K
Acute Pyelonephritis I: Introduction01:27

Acute Pyelonephritis I: Introduction

1.1K
Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such...
1.1K
Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

628
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
628
Urinary Tract Infection II: Pathophysiology01:25

Urinary Tract Infection II: Pathophysiology

1.1K
The pathophysiology of urinary tract infections (UTIs) encompasses several progressive stages, beginning with bacterial colonization and culminating in potential systemic complications if untreated. UTIs are primarily initiated by bacteria, such as Escherichia coli, which often originate from the gastrointestinal tract and migrate to the urinary system through the periurethral area. This migration can occur via several routes, including improper hygiene practices, sexual activity, or...
1.1K
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care01:30

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

393
A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
393
Urinary Tract Infection IV: Nursing Management01:17

Urinary Tract Infection IV: Nursing Management

592
In managing urinary tract infections (UTIs) in nursing, a comprehensive assessment is essential. Begin by gathering subjective data, such as the patient’s complaints of dysuria (painful urination), urinary frequency, urgency, suprapubic pain, and any lower abdominal discomfort. This information can be complemented by questions regarding previous UTIs, sexual activity, and personal hygiene practices, which can provide insight into risk factors. Objective assessment should focus on signs...
592

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Shared multicellular injury programs of acute and chronic kidney disease enable mechanistic patient stratification.

medRxiv : the preprint server for health sciences·2026
Same author

Case Series of Histopathological Findings in Chronic Kidney Disease: Insights From the Kidney Precision Medicine Project.

Kidney medicine·2026
Same author

Monoclonal Immunotactoid Glomerulopathy Associated With Chronic Lymphocytic Leukemia: A Case Report.

Cureus·2025
Same author

Temporal and Demographic Trends in Biopsy-Proven Kidney Disease Diagnoses in the Southwestern United States, 1993-2022.

Kidney medicine·2025
Same author

Seeing the light (chains): a paradigm shift in PGNMID.

Kidney international·2025
Same author

Late BK Nephropathy 15 years post kidney transplant following chemotherapy: A case report.

IDCases·2025
Same journal

Molecular Pathology in Contemporary Surgical Practice.

Surgical pathology clinics·2026
Same journal

Beyond Blood: Liquid biopsy assays for nonplasma body fluids.

Surgical pathology clinics·2026
Same journal

The Molecular Landscape of Ovarian Neoplasms: A Review.

Surgical pathology clinics·2026
Same journal

Clinically Relevant Molecular Pathology of Endometrial Cancer.

Surgical pathology clinics·2026
Same journal

Molecular Pathology of Genitourinary Tumors: Diagnostic, Prognostic, and Therapeutic Implications.

Surgical pathology clinics·2026
Same journal

Oncogenicity and Therapeutic Implications of Molecular Biomarkers in Colorectal Carcinoma.

Surgical pathology clinics·2026
See all related articles

Related Experiment Video

Updated: Mar 26, 2026

Intrarenal Injection of Escherichia coli in a Rat Model of Pyelonephritis
06:09

Intrarenal Injection of Escherichia coli in a Rat Model of Pyelonephritis

Published on: July 18, 2017

8.7K

Renal Infections.

Jean Hou1, Leal C Herlitz2

  • 1Department of Pathology and Cell Biology, Columbia University Medical Center, New York Presbyterian Hospital, VC14-224, New York, NY 10032, USA.

Surgical Pathology Clinics
|February 4, 2016
PubMed
Summary
This summary is machine-generated.

This review details gross and histologic findings in kidney infections caused by bacteria, viruses, fungi, and mycobacteria. Accurate diagnosis is essential for effective treatment, distinguishing infections from other kidney conditions.

Keywords:
Acute pyelonephritisChronic pyelonephritisFungal pyelonephritisMalacoplakiaPolyomavirus nephropathyViral interstitial nephritisXanthogranulomatous pyelonephritis

More Related Videos

Establishment and Characterization of UTI and CAUTI in a Mouse Model
08:40

Establishment and Characterization of UTI and CAUTI in a Mouse Model

Published on: June 23, 2015

21.2K
Isolation of Single Intracellular Bacterial Communities Generated from a Murine Model of Urinary Tract Infection for Downstream Single-cell Analysis
07:34

Isolation of Single Intracellular Bacterial Communities Generated from a Murine Model of Urinary Tract Infection for Downstream Single-cell Analysis

Published on: April 16, 2019

8.7K

Related Experiment Videos

Last Updated: Mar 26, 2026

Intrarenal Injection of Escherichia coli in a Rat Model of Pyelonephritis
06:09

Intrarenal Injection of Escherichia coli in a Rat Model of Pyelonephritis

Published on: July 18, 2017

8.7K
Establishment and Characterization of UTI and CAUTI in a Mouse Model
08:40

Establishment and Characterization of UTI and CAUTI in a Mouse Model

Published on: June 23, 2015

21.2K
Isolation of Single Intracellular Bacterial Communities Generated from a Murine Model of Urinary Tract Infection for Downstream Single-cell Analysis
07:34

Isolation of Single Intracellular Bacterial Communities Generated from a Murine Model of Urinary Tract Infection for Downstream Single-cell Analysis

Published on: April 16, 2019

8.7K

Area of Science:

  • Nephrology
  • Pathology
  • Infectious Diseases

Background:

  • Renal infections present diverse gross and histologic features.
  • Distinguishing infections from inflammatory or neoplastic conditions is critical for patient management.
  • A comprehensive understanding aids in accurate diagnosis and targeted therapy.

Purpose of the Study:

  • To review gross and histologic findings in various renal infections.
  • To emphasize the differential diagnosis of renal infections.
  • To highlight key features that differentiate infection from mimics.

Main Methods:

  • Review of literature on renal infections.
  • Compilation of gross and histologic findings for bacterial, viral, fungal, and mycobacterial infections.
  • Discussion of diagnostic criteria and differential diagnoses.

Main Results:

  • Detailed descriptions of acute and chronic bacterial pyelonephritis.
  • Characterization of xanthogranulomatous pyelonephritis and malacoplakia.
  • Overview of viral, fungal, and mycobacterial renal infections.

Conclusions:

  • Accurate identification of renal infections based on pathologic findings is paramount.
  • Differential diagnosis is crucial to avoid misclassification with non-infectious renal diseases.
  • This review provides a resource for pathologists and clinicians managing renal infections.