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Nitrofurantoin-induced acute pulmonary toxicity.
Konstantinos Livanios1, Eirini-Sofia Karampi1, Adamantia Sotiriou1
110th Clinic of Pulmonary Medicine Hospital of Chest Disease "Sotiria" Athens Greece.
Respirology Case Reports
|February 4, 2016
Summary
A woman developed severe acute respiratory failure due to nitrofurantoin, a common antibiotic. This case highlights the importance of considering drug-induced lung injury in patients with respiratory distress.
Area of Science:
- Pulmonology
- Pharmacology
- Toxicology
Background:
- Nitrofurantoin is a widely prescribed antibiotic for urinary tract infections.
- Acute pulmonary toxicity is a rare but serious adverse effect of nitrofurantoin therapy.
Observation:
- A female patient presented with fever and acute respiratory failure.
- Exhaustive investigations ruled out other common causes of respiratory distress.
Findings:
- The patient was diagnosed with nitrofurantoin-induced acute pulmonary toxicity.
- This diagnosis was made after excluding infectious, cardiac, and autoimmune etiologies.
Implications:
- Clinicians should consider drug-induced lung injury in patients presenting with unexplained respiratory failure.
- Early recognition and cessation of the offending agent are crucial for patient outcomes.
- This case underscores the need for vigilance regarding potential adverse drug reactions to commonly used medications.
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