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Mediator Architecture and RNA Polymerase II Interaction

Clemens Plaschka1, Kayo Nozawa1, Patrick Cramer1

  • 1Max Planck Institute for Biophysical Chemistry, Department of Molecular Biology, Am Fassberg 11, 37077, Göttingen, Germany.

Journal of Molecular Biology
|February 7, 2016
PubMed
Summary

Recent advances in structural biology reveal the architecture of the Mediator complex and its interaction with RNA polymerase II. Further research is needed to understand Mediator structure and function.

Keywords:
RNA polymerase IIcoactivatorgene transcriptionmultiprotein complex

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