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Updated: Mar 26, 2026
Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT
Published on: January 22, 2018
FDG PET/CT in Sarcomatoid Carcinoma of the Gallbladder With Chondroid Differentiation
Aisheng Dong1, Hui Dong, Wei Jing
1From the *Department of Nuclear Medicine, Changhai Hospital; †Department of Pathology, Eastern Hepatobiliary Surgery Hospital; and ‡Department of General Surgery, Changhai Hospital, Second Military Medical University, Shanghai, China.
Abstract:
Sarcomatoid carcinoma of the gallbladder, composed of epithelial and sarcomatous components, is a rare malignant tumor with a poor prognosis. A 61-year-old man was admitted because of abdominal distention for 2 weeks. Enhanced CT showed a large gallbladder tumor with central necrosis. The tumor measuring 18 cm in maximum diameter showed intense peripheral FDG uptake with SUVmax of 15.4. The specimen of the resected tumor revealed tubular adenocarcinoma and sarcomatoid tissue with chondroid differentiation. Immunohistochemical staining showed the sarcomatoid tissue was positive for EMA, CD10, and VIM, with proliferation index of 80%. These pathologic findings were consistent with sarcomatoid carcinoma.
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