Related Experiment Videos

Lactate dehydrogenase isoenzymes in myocardial disease

P L Wolf1

  • 1University of California Medical Center, San Diego.

Insights

Serum lactate dehydrogenase (LD) levels increase in myocardial diseases, showing a specific isoenzyme pattern. This ubiquitous enzyme

Area of Science:

  • Biochemistry
  • Cardiology
  • Enzymology

Background:

  • Serum lactate dehydrogenase (LD) is a marker observed to be elevated in various myocardial diseases.
  • A distinct pattern of LD isoenzyme elevation is characteristic of myocardial conditions.

Purpose of the Study:

  • To analyze the elevation patterns of serum lactate dehydrogenase (LD) in myocardial diseases.
  • To discuss the implications of LD isoenzyme patterns in diagnosing cardiac conditions.
  • To review other conditions associated with elevated serum LD.

Main Methods:

  • Analysis of serum lactate dehydrogenase (LD) levels.
  • Examination of LD isoenzyme patterns.
  • Review of clinical data from patients with various diseases.

Main Results:

  • Serum lactate dehydrogenase (LD) elevation is confirmed in multiple myocardial diseases.
  • A specific LD isoenzyme profile is associated with myocardial disease.
  • Elevated serum LD is also observed in a wide range of non-cardiac diseases.

Conclusions:

  • Serum lactate dehydrogenase (LD) and its isoenzymes are valuable indicators in myocardial disease diagnosis.
  • The ubiquitous nature of LD means elevated levels can occur in numerous conditions, requiring careful interpretation.

Related Concept Videos