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Updated: Mar 25, 2026

A General Method for Detecting Nitrosamide Formation in the In Vitro Metabolism of Nitrosamines by Cytochrome P450s
Published on: September 25, 2017
[THE LEVEL OF NAPHTHALENE AND ITS DERIVATES IN TOBACCO SMOKE]
D Zurabashvili1, G Parulava1, Z Gvishiani1
1Center of Mental Health and Prevention of Addition, Tbilisi; Georgian State Teaching University of Physical Education and Sport, Tbilisi, Georgia.
Abstract:
The composition of cigarette smoke in spite of its tremendous complexity is relatively known, but little is known about the influence of Ecologic Factors (air flows, temperature, light) on the Migration Character of individual and specific components of Tobacco Smoke constansate in environmental atmosphere on different distance from burning cigarette. Oxidation in air, and photochemical reactions can produce many compounds which were not originally present in the Tobacco Smoke. Gas liquid Chromatography with high-resolution capillary column is applied. The tobacco skome volume was taked and analyzed in the distance of 2,0 m and 4,0 m from burning cigarette. The content of naphthalene and its derivates in the air samples was revealed. Our data show that distance of exposition from burning cigarette can change the structure and volume of each component of tobacco smoke. The studies are necessary in different direction. First, this phenomen still needs to be explained. The second, it would be interesting to investigate the retention of tobacco smoke components in lung tissue, for a considerable time after the smoking process. The obtained data is very important from the point of ecological assessment of the environment and sensitivity to the components of tobacco smoke.
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