Related Experiment Video
Updated: Mar 25, 2026

06:26
Quantitative Assessment Protocol for Facial Soft Tissue Volumetric Changes with Stereophotogrammetry
Published on: December 9, 2025
272
Relation between soft tissue and skeletal changes after mandibular setback surgery: A systematic review and
Eleftherios G Kaklamanos1, Olga-Elpis Kolokitha2
1Hamdan Bin Mohammed College of Dental Medicine, Mohammed Bin Rashid University of Medicine & Health Sciences, P.O. Box 505097 Dubai, United Arab Emirates.
Summary
Predicting soft and hard tissue changes in orthognathic surgery is crucial. This study found strong correlations between hard and soft tissue movements after mandibular setback, offering initial clinical guidance.
Area of Science:
- Oral and Maxillofacial Surgery
- Orthodontics
- Plastic Surgery
Background:
- Accurate prediction of hard and soft tissue changes is vital for successful orthognathic surgery outcomes.
- Mandibular setback surgery requires precise understanding of skeletal and soft tissue responses.
Purpose of the Study:
- To systematically investigate the relationship between soft and hard tissue relocation following mandibular setback surgery.
- To provide clinically relevant guidance on soft to hard tissue movement ratios.
Main Methods:
- Systematic literature search for studies reporting soft and hard tissue changes after mandibular setback.
- Extraction of correlation coefficients and ratios; assessment of risk of bias.
- Meta-analysis using the random effects model to combine data from eligible studies.
Main Results:
- Five studies were included, demonstrating high correlations between sagittal hard tissue changes (pogonion, point B, incisal inferius) and corresponding soft tissue movements.
- Soft to hard tissue movement ratios ranged from 0.915 to 1.051.
- Only two studies had a moderate risk of bias, indicating potential limitations in the evidence base.
Conclusions:
- The study provides initial, clinically relevant guidance on soft to hard tissue movement ratios after mandibular setback.
- The limited number of studies and their characteristics necessitate further long-term, standardized, and well-conducted trials for definitive conclusions.

