Related Experiment Video
Updated: Mar 25, 2026
Studying Orthodontic Tooth Movement in Mice
Published on: August 2, 2024
Minimally Invasive Techniques to Accelerate the Orthodontic Tooth Movement: A Systematic Review of Animal Studies
Irfan Qamruddin1, Mohammad Khursheed Alam2, Mohd Fadhli Khamis3
1Orthodontic Department, Baqai Medical University, P.O. Box 2407, Karachi, Pakistan.
Objective:
To evaluate various noninvasive and minimally invasive procedures for the enhancement of orthodontic tooth movement in animals.
Materials And Methods:
Literature was searched using NCBI (PubMed, PubMed Central, and PubMed Health), MedPilot (Medline, Catalogue ZB MED, Catalogue Medicine Health, and Excerpta Medica Database (EMBASE)), and Google Scholar from January 2009 till 31 December 2014. We included original articles related to noninvasive and minimally invasive procedures to enhance orthodontic tooth movement in animals. Extraction of data and quality assessments were carried out by two observers independently.
Results:
The total number of hits was 9195 out of which just 11 fulfilled the inclusion criteria. Nine articles were good and 5 articles were moderate in quality. Low level laser therapy (LLLT) was among the most common noninvasive techniques whereas flapless corticision using various instruments was among the commonest minimally invasive procedures to enhance velocity of tooth movement.
Conclusions:
LLLT, low intensity pulsed ultrasound (LIPUS), mechanical vibration, and flapless corticision are emerging noninvasive and minimally invasive techniques which need further researches to establish protocols to use them clinically with conviction.
