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Selective biotransformations. Patents and literature
1Department of Chemical and Materials Engineering, University of Iowa, Iowa City 52242.
Applied Biochemistry and Biotechnology
|December 1, 1989
Summary
Biocatalysis enables selective organic synthesis using microorganisms and enzymes. Recent advancements in genetic engineering and organic media enhance these stereo- and regioselective biotransformations.
Area of Science:
- Organic Chemistry
- Biotechnology
- Enzymology
Context:
- Stereo- and regioselective biotransformations are crucial in organic synthesis.
- Microorganisms and isolated enzymes are established tools for selective synthesis.
- Recent advancements have accelerated research in selective biotransformations.
Purpose:
- To survey recent US patents and scientific literature on stereo- and regioselective biotransformations.
- To summarize key patent abstracts and provide literature references.
- To highlight novel methodologies driving progress in the field.
Summary:
- The field of selective biotransformations is rapidly advancing due to new techniques.
- These include genetic and protein engineering, biocatalysis in organic media, and improved screening.
- Biotechnology's value in solving organic synthesis problems is increasingly recognized.
Impact:
- Provides a comprehensive overview of recent developments in selective biotransformations.
- Offers insights into patent landscapes and scientific literature.
- Facilitates further research and application of biocatalysis in organic synthesis.