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Updated: Mar 25, 2026

06:15
A Hydrogel Construct and Fibrin-based Glue Approach to Deliver Therapeutics in a Murine Myocardial Infarction Model.
Published on: June 14, 2015
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A peptide hydrogel derived from a fragment of human cardiac troponin C
Luis M De Leon-Rodriguez1, Meder Kamalov2, Yacine Hemar2
1School of Biological Sciences, The University of Auckland, 3 Symonds St, Auckland, New Zealand. l.deleon@auckland.ac.nz m.brimble@auckland.ac.nz.
Abstract:
The human cardiac troponin C peptide fragment H-V(9)EQLTEEQKNEFKAAFDIFVLGA(31)-OH, which covers helix-A in the native protein, self-assembles into β-sheet fibrils in solution. These fibrils further entangle to give a hydrogel. This peptide may therefore serve as a template for development of novel biomaterials.

