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Updated: Mar 25, 2026

Mouse Models of Epididymitis Induced by Pathogen-Associated Molecular Patterns
Published on: December 12, 2025
[EPIDIDYMO-ORCHITIS IN PREPUBERTAL CHILDREN--PREVALENCE, ETIOLOGY, SUGGESTED DIAGNOSIS ALGORITHM]
Abstract:
Gonadal inflammation (GI) is a common disease that may affect prepubertal boys. Neonates may suffer from bacterial infection due to congenital or aging processes affecting the urinary tract. This inflammatory process is also prevalent in prepubertal boys. However, in this group, the etiology, the needed imaging modalities and proper management have not yet been clearly defined. This manuscript will systematically review the various etiologies causing GI in pre-pubertal boys, discuss the proper imaging needed, and image interpretation and will provide treatment and follow-up recommendations.
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