Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Clinical Trials01:16

Clinical Trials

11.1K
Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
11.1K
Clinical Trials: Overview01:11

Clinical Trials: Overview

5.4K
Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
5.4K
Statistical Software for Data Analysis and Clinical Trials01:12

Statistical Software for Data Analysis and Clinical Trials

1.8K
Statistical software is pivotal in data analysis and clinical trials by providing tools to analyze data, draw conclusions, and make predictions. These software packages range from simple data management applications to complex analytical platforms, supporting various statistical tests, models, and simulation techniques. Their significance lies in their ability to handle vast amounts of data with precision and efficiency, enabling researchers to validate hypotheses, identify trends, and make...
1.8K
Data Collection by Experiments01:13

Data Collection by Experiments

28.0K
Data collection is a systematic method of obtaining, observing, measuring, and analyzing accurate information. An experimental study is a standard method of data collection that involves the manipulation of the samples by applying some form of treatment prior to data collection. It refers to manipulating one variable to determine its changes on another variable. The sample subjected to treatment is known as “experimental units.”
An example of the experimental method is a public...
28.0K
Therapeutic Drug Monitoring: Affecting Factors01:29

Therapeutic Drug Monitoring: Affecting Factors

324
Therapeutic Drug Monitoring (TDM) is the clinical practice of measuring specific drug levels in a patient's blood or body tissues to manage and optimize therapy. TDM is crucial for drugs with narrow therapeutic windows, like warfarin and phenytoin, where incorrect doses can lead to treatment failure or severe side effects. This monitoring ensures the dosage administered is within a safe and effective range. The factors affecting therapeutic drug monitoring include:Patient-Specific Factors:a.
324
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

520
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
520

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Knockout of OsRbohD (the NADPH Oxidase Gene) Enhances Saline-Alkaline Stress Tolerance and Grain Yield in Rice by Reducing ROS Accumulation.

Rice (New York, N.Y.)·2026
Same author

Semirandom DNA adducts regulate a filamentous defense-associated reverse transcriptase.

Nature structural & molecular biology·2026
Same author

Regulation of exosomal miR-513a and miR-149 expression by APE1 in PD-L1 and TCR immune regulation pathways to promote immune evasion in osteosarcoma.

Cancer genetics·2026
Same author

Systematic screening of archaeal MazF homologs reveals Tth-MazF1, a versatile, sequence-specific ribonuclease from Thermococcus thioreducens.

Nucleic acids research·2026
Same author

Innovative use of a long transparent cap for closure of large duodenal defects post endoscopic full-thickness resection: a case report.

iGIE : innovation, investigation and insights·2026
Same author

Clinical outcomes of circumferential endoscopic submucosal dissection for superficial esophageal squamous cell carcinoma: a retrospective study.

Gastrointestinal endoscopy·2026
Same journal

[The protective effects of curcumin loaded mesoporous silica nanoparticles on rat cardiomyocytes].

Yao xue xue bao = Acta pharmaceutica Sinica·2018
Same journal

[Identification of water buffalo horn and its adulterants using COI barcode].

Yao xue xue bao = Acta pharmaceutica Sinica·2018
Same journal

[Construction of the brain-targeting drug carrier through imprinting of nicotinic acetylcholine receptor α7].

Yao xue xue bao = Acta pharmaceutica Sinica·2018
Same journal

[Application of magnetic iron oxide nanoparticles in magnetic resonance / photothermal dual-modal imaging].

Yao xue xue bao = Acta pharmaceutica Sinica·2018
Same journal

[Endocytosis pathway and intracellular distribution of heparosan].

Yao xue xue bao = Acta pharmaceutica Sinica·2018
Same journal

[On-line detection of concentration process of Ganmaoling granules by near infrared spectroscopy combined with automatic control system].

Yao xue xue bao = Acta pharmaceutica Sinica·2018
See all related articles

Related Experiment Video

Updated: Mar 25, 2026

Generation of Comprehensive Thoracic Oncology Database - Tool for Translational Research
11:18

Generation of Comprehensive Thoracic Oncology Database - Tool for Translational Research

Published on: January 22, 2011

16.5K

[Key issues on the clinical trial data management].

Ping-yan Chen, Yu Xu, Nan Dai

    Yao Xue Xue Bao = Acta Pharmaceutica Sinica
    |February 26, 2016
    PubMed
    Summary
    This summary is machine-generated.

    This study addresses common challenges in clinical data management, focusing on team building, standard procedures, and quality improvement strategies for efficient clinical trials.

    More Related Videos

    Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index
    06:55

    Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index

    Published on: January 8, 2020

    15.5K
    A Clinical Trial Assessing the Safety, Efficacy, and Delivery of Olive-Oil-Based Three-Chamber Bags for Parenteral Nutrition
    04:53

    A Clinical Trial Assessing the Safety, Efficacy, and Delivery of Olive-Oil-Based Three-Chamber Bags for Parenteral Nutrition

    Published on: September 20, 2019

    11.4K

    Related Experiment Videos

    Last Updated: Mar 25, 2026

    Generation of Comprehensive Thoracic Oncology Database - Tool for Translational Research
    11:18

    Generation of Comprehensive Thoracic Oncology Database - Tool for Translational Research

    Published on: January 22, 2011

    16.5K
    Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index
    06:55

    Inverse Probability of Treatment Weighting Propensity Score using the Military Health System Data Repository and National Death Index

    Published on: January 8, 2020

    15.5K
    A Clinical Trial Assessing the Safety, Efficacy, and Delivery of Olive-Oil-Based Three-Chamber Bags for Parenteral Nutrition
    04:53

    A Clinical Trial Assessing the Safety, Efficacy, and Delivery of Olive-Oil-Based Three-Chamber Bags for Parenteral Nutrition

    Published on: September 20, 2019

    11.4K

    Area of Science:

    • Clinical Data Management
    • Clinical Trial Operations
    • Data Governance

    Background:

    • Effective data management is crucial for successful clinical trials.
    • Numerous challenges can impede data quality and trial efficiency.
    • Addressing these issues requires a systematic approach.

    Purpose of the Study:

    • To identify and discuss prevalent issues in clinical data management.
    • To propose strategies for enhancing data management practices.
    • To improve the overall quality and efficiency of clinical trials.

    Main Methods:

    • Literature review of common data management challenges.
    • Analysis of key areas including team development, SOPs, and documentation.
    • Discussion of error correction, prevention, and quality improvement measures.

    Main Results:

    • Identified key issues in team building, SOPs, document control, and communication.
    • Outlined strategies for mistake correction and prevention.
    • Highlighted measures to boost quality and efficiency in clinical trial data management.

    Conclusions:

    • Systematic attention to data management processes is essential for trial success.
    • Proactive strategies for team training and procedural standardization improve data integrity.
    • Continuous quality improvement is vital for efficient and reliable clinical research.