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Preparation of Binary and Ternary Deep Eutectic Systems
Published on: October 31, 2019
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Efficient continuous synthesis of high purity deep eutectic solvents by twin screw extrusion
D E Crawford1, L A Wright2, S L James1
1School of Chemistry and Chemical Engineering, Queen's University Belfast, 39 - 123 Stranmillis Road, Belfast, BT9 5AG, Northern Ireland, UK. s.james@qub.ac.uk.
Chemical Communications (Cambridge, England)
|February 26, 2016
Summary
Mechanochemical synthesis using Twin Screw Extrusion rapidly produces high-purity Deep Eutectic Solvents (DESs). This continuous flow method offers significantly higher Space Time Yields (STYs) compared to traditional batch synthesis.
Area of Science:
- Green Chemistry
- Materials Science
- Chemical Engineering
Background:
- Deep Eutectic Solvents (DESs) are versatile materials with tunable properties.
- Traditional synthesis of DESs can be time-consuming and inefficient.
- Mechanochemical synthesis offers a solvent-free and rapid alternative.
Purpose of the Study:
- To investigate the rapid synthesis of Deep Eutectic Solvents (DESs) using mechanochemistry.
- To explore the application of continuous flow Twin Screw Extrusion (TSE) for DES production.
- To compare the efficiency and purity of TSE-synthesized DESs with batch methods.
Main Methods:
- Mechanochemical synthesis utilizing Twin Screw Extrusion (TSE) in a continuous flow setup.
- Synthesis of Reline 200 (choline chloride:urea, 1:2) as a model DES.
- Analysis of product purity and Space Time Yields (STYs).
Main Results:
- Successful rapid synthesis of DESs, including Reline 200, via continuous flow TSE.
- Achieved higher product purity compared to conventional batch synthesis.
- Demonstrated Space Time Yields (STYs) four orders of magnitude greater than batch methods.
Conclusions:
- Continuous flow mechanochemical synthesis using TSE is a highly efficient method for DES production.
- TSE offers a scalable and environmentally friendly approach to synthesizing high-purity DESs.
- This methodology significantly enhances productivity for DES manufacturing.
