Related Experiment Videos
A mutation of Streptomyces lividans which prevents intraplasmid recombination has no effect on chromosomal
H M Kieser1, D J Henderson, C W Chen
1John Innes Institute, Norwich, UK.
Molecular & General Genetics : MGG
|December 1, 1989
Abstract:
A mutation (rec-46) of Streptomyces lividans, previously shown to prevent (or greatly diminish) homologous and illegitimate intraplasmid recombination, was shown to have no effect on generalised chromosomal recombination occurring in matings or in protoplast fusions, nor to affect homologous recombination between a recombinant plasmid and the host chromosome. By comparison with Escherichia coli mutants defective in various aspects of recombination, the rec-46 mutation is similar to those in recF, recJ, recO and topA.