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[ASSESSMENT OF QOL BY URTICARIA ACTIVITY SCORE IN PEDIATRIC PATIENTS WITH CHRONIC URTICARIA]
Tomoyuki Asaumi1, Katsuhito Iikura, Noriyuki Yanagida
1Department of Pediatrics, Sagamihara National Hospital.
Insights
The Japanese Urticaria Activity Score (UAS) effectively assesses quality of life in children with chronic urticaria. This tool helps track disease severity and its impact on daily living.
Area of Science:
- Pediatric Dermatology
- Allergy and Immunology
- Quality of Life Assessment
Context:
- Lack of a standardized method for assessing pediatric chronic urticaria in Japan.
- Established correlation between Urticaria Activity Score (UAS) and Dermatology Life Quality Index (DLQI).
- European Academy of Allergy and Clinical Immunology (EAACI) guidelines recommend UAS for chronic urticaria assessment.
Purpose:
- Translate the UAS into Japanese for pediatric use.
- Evaluate the usefulness of the Japanese UAS by comparing it with quality of life scores.
- Establish a reliable tool for assessing pediatric chronic urticaria in Japan.
Summary:
- 42 pediatric patients with chronic urticaria completed the Japanese UAS at home and the Children's Dermatology Life Quality Index (CDLQI) during clinic visits.
- Analysis revealed a correlation between UAS7 (weekly UAS totals) and CDLQI scores.
- Results indicate that UAS7 values reflect and changes in UAS7 values mirror changes in the quality of life impairment experienced by pediatric chronic urticaria patients.
Impact:
- The Japanese UAS is a potentially valuable tool for assessing quality of life in pediatric patients with chronic urticaria.
- Provides a standardized method for evaluating disease activity and its impact on QOL in Japanese children.
- Facilitates better management and understanding of chronic urticaria in pediatric populations.
Background:
There is no standard for assessing pediatric chronic urticaria in Japan. UAS7, weekly total values of the Urticaria Activity Score (UAS), has correlation with Dermatology Life Quality Index (DLQI) which assesses Quality of Life (QOL). The current European Academy of Allergy and Clinical Immunology (EAACI) guidelines recommend assessing disease activity in chronic urticaria by using UAS. We translated UAS into Japanese version, and evaluated usefulness of UAS by comparing with QOL score.
Methods:
Subjects were 42 patients who had received treatments in our clinic from February to September in 2014. They wrote UAS at home. They wrote Children's Dermatology Life Quality Index (CDLQI) when they visited hospital. We assessed correlation UAS7 with CDLQI.
Results:
Male/Female ratio was 1:1. Median age was 7.5 years old. Duration of chronic urticaria was 5.5 months. Anti-histamine was used in 75%. UAS7 values reflected chronic urticaria patients' quality of life impairment. Change in UAS7 values reflected change in chronic urticaria patients' quality of life impairment.
Conclusion:
UAS may be a useful tool for assessing QOL in pediatric patients with chronic urticaria.
