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Updated: Mar 25, 2026

Author Spotlight: Emerging Technologies and Advanced Tools for Decoding Metabolomics Data Analysis
Published on: November 10, 2023
[Lifestyle-related diseases and an inter-organ metabolic network]
Yasutaka Miyachi1, Kyoichiro Tsuchiya1, Yoshihiro Ogawa1
1Department of Molecular Endocrinology and Metabolism,Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Japan.
Abstract:
Lifestyle-related diseases such as type 2 diabetes, hypertension and dyslipidemia are a prominent cause of mortality in Japan, and there is a strong requirement for elucidation of detailed molecular mechanisms and effective therapeutic strategies. Obesity-induced adipose tissue inflammation leads to dysregulation of adipokine production, which can cause lifestyle-related diseases. The interaction of organ systems via endocrine or neural networks is recognized as an important factor in the pathogenesis and promotion of lifestyle-related diseases. Therefore, further investigation for the interaction between adipose tissues and bones can provide new treatment strategies of metabolic bone disorders.
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