Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Major Hormones and Their Functions01:27

Major Hormones and Their Functions

2.7K
Hormones, the biochemical messengers produced by endocrine glands, are pivotal in regulating bodily functions and maintaining homeostasis. Each hormone's balance is crucial; imbalances can lead to significant physiological disruptions. Major hormones include oxytocin, cortisol, epinephrine, estrogen, testosterone, thyroxine, growth hormone, insulin, and glucagon.
Oxytocin, produced in the hypothalamus and released by the pituitary gland, plays a role in social bonding, childbirth, and...
2.7K
Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

8.8K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
8.8K
Functions of Thyroid Hormones01:18

Functions of Thyroid Hormones

6.5K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
6.5K
Psychosis and Antipsychotic Drugs: Overview01:28

Psychosis and Antipsychotic Drugs: Overview

1.1K
The term "psychosis" refers to a spectrum of mental disorders characterized by abnormal thoughts, perceptions, and behaviors. It can manifest as mood disorders, dementia, delirium with psychotic features, substance-induced psychosis with psychotic features, brief psychotic disorder, delusional disorder, schizoaffective disorder, and schizophrenia. Among all these disorders, schizophrenia is the most common psychotic disorder, affecting 1% of the worldwide population. Psychotic...
1.1K
Bipolar Disorder01:30

Bipolar Disorder

1.3K
Bipolar disorder is a chronic mental health condition marked by significant mood fluctuations, including episodes of mania and depression. Elevated energy levels, heightened mood or irritability, impulsive behavior, reduced sleep needs, rapid speech, racing thoughts, inflated self-esteem, and distractibility characterize mania. Individuals with bipolar disorder often alternate between depressive and manic states, with periods of emotional stability lasting an average of six months to a year.
1.3K
Mania and Antimanic Drugs: Overview01:24

Mania and Antimanic Drugs: Overview

756
Mania, a psychological condition characterized by elevated mood, increased energy, and reduced sleep need, is part of the bipolar disorder cycle. The exact cause of mania isn't entirely known, but it is thought to be a combination of genetic, environmental, and neurological factors. Bipolar disorder involves alternating manic and depressive episodes. Mood stabilizers like lithium, antipsychotics, and anticonvulsants help manage these episodes. Lithium carbonate is particularly effective as...
756

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sensory alterations and immunological changes during the chronification of postsurgical pain: a study protocol for a prospective observational cohort study.

BMJ open·2025
Same author

Primary intra-articular epithelioid sarcoma of the knee: Unusual presentation of a rare entity.

Journal of orthopaedics·2018
Same author

Panic disorder and depression: relationship between psychological and biochemical aspects.

Acta neuropsychiatrica·2016
Same author

Neuropsychiatrie aspects of HIV infection.

Acta neuropsychiatrica·2016
Same author

Treatmentstrategies in refractory panic disorder.

Acta neuropsychiatrica·2016
Same author

Norharman and anxiety disorders.

Acta neuropsychiatrica·2016
Same journal

Serum Levels of IFN-γ and NGF as Potential Biomarkers of Depressive Disorders.

Acta neuropsychiatrica·2026
Same journal

The Danish Region Midt Schizophrenia Cohort - Representative, long-term follow-up of first-episode schizophrenia spectrum disorder.

Acta neuropsychiatrica·2026
Same journal

The effects of psychedelics on attention deficit and hyperactivity disorder - a systematic review.

Acta neuropsychiatrica·2026
Same journal

Breaking down the ADHD construct to build a valid diagnosis.

Acta neuropsychiatrica·2026
Same journal

A comprehensive systematic review of human trials investigating herbal treatments for Alzheimer's disease and dementia.

Acta neuropsychiatrica·2026
Same journal

Age-dependent increase in peripheral neuropeptide Y with no cross-sectional link to depression.

Acta neuropsychiatrica·2026
See all related articles

Related Experiment Video

Updated: Mar 24, 2026

Author Spotlight: Accurately Assessing Thyroid Hormone-Driven Motor Alterations in Mouse
04:05

Author Spotlight: Accurately Assessing Thyroid Hormone-Driven Motor Alterations in Mouse

Published on: October 6, 2023

829

Thyroid function and psychiatric disorders.

P J Schoof1, L Timmerman2, E J Colon1

  • 1Deltaziekenhuis,Poortugaal.

Acta Neuropsychiatrica
|March 10, 2016
PubMed
Summary
This summary is machine-generated.

Psychiatric illnesses may influence thyroxine levels, with elevated thyroxine (thyroid hormone) found in 13.5% of psychiatric patients. Schizophrenia and psychotic disorders were more prevalent in patients with high thyroxine concentrations.

More Related Videos

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
04:39

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model

Published on: March 17, 2023

2.6K
Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression
04:33

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression

Published on: April 26, 2024

1.6K

Related Experiment Videos

Last Updated: Mar 24, 2026

Author Spotlight: Accurately Assessing Thyroid Hormone-Driven Motor Alterations in Mouse
04:05

Author Spotlight: Accurately Assessing Thyroid Hormone-Driven Motor Alterations in Mouse

Published on: October 6, 2023

829
Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
04:39

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model

Published on: March 17, 2023

2.6K
Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression
04:33

Author Spotlight: Unveiling the Connection Between Sleep Disorders and Cognitive Symptoms in Depression

Published on: April 26, 2024

1.6K

Area of Science:

  • Endocrinology
  • Psychiatry
  • Clinical Medicine

Background:

  • Thyroxine concentration is a critical indicator of thyroid function.
  • The relationship between psychiatric disorders and thyroid function requires further investigation.
  • Altered thyroid hormone levels can manifest with psychiatric symptoms.

Purpose of the Study:

  • To investigate the potential influence of psychiatric illnesses on thyroxine concentration.
  • To determine the prevalence of abnormal thyroxine levels in psychiatric patients.
  • To explore the association between specific psychiatric diagnoses and thyroxine levels.

Main Methods:

  • Retrospective study of 376 patients admitted to a psychiatric hospital.
  • Analysis of thyroxine concentrations (elevated, normal, low).
  • Comparison of thyroxine levels across different psychiatric diagnoses.

Main Results:

  • 13.5% of patients exhibited elevated thyroxine concentration; only 0.6% had low concentration.
  • Elevated thyroxine was significantly more common in men (22.8%) than women (6.6%).
  • Schizophrenia (19.6%) and psychotic disorders NOS (17.4%) were more frequent in patients with elevated thyroxine compared to those with normal levels (4.4% and 6.5%).

Conclusions:

  • Specific psychiatric illnesses, particularly schizophrenia and psychotic disorders, are associated with elevated thyroxine concentrations.
  • Abnormal thyroxine levels are relatively common in psychiatric inpatients.
  • Further research is warranted to understand the bidirectional relationship between thyroid function and mental health.