Related Experiment Video
Updated: Mar 24, 2026

Low-Dose Gamma Radiation Sterilization for Decellularized Tracheal Grafts
Published on: April 14, 2023
Effect of Cuff Pressure Elevation on Internal Diameter of Tracheal Tube in Simulated Trachea
Yukiko Matsuki1, Nobuyuki Matsuura, Tatsuya Ichinohe
1Department of Dental Anesthesiology, Chiba Hospital of Tokyo Dental College.
Abstract:
Application of nitrous oxide during anesthesia causes an increase in tracheal tube cuff pressure over time. The purpose of this study was to investigate the effect of an increase in cuff pressure on 3 types of tube (the Portex, Mallinckrodt, and Parker) commonly used for nasotracheal intubation. A cylindrical vessel was used to simulate a trachea. Cuff pressure was set at 0 cmH2O (R0) or 20 cmH2O (R20) at room temperature, or at 20 cmH2O (H20), 40 cmH2O (H40), 60 cmH2O (H60), or 80 cmH2O (H80) in 38°C hot water and pressure applied for 30 min. The value obtained at R0 was used as a reference (100%) and the rate of change under each condition determined. No change was observed at R20 in any of the 3 groups. In 38°C hot water, internal diameter in the Portex group decreased by 5.4% at H20 and 7.3% at H40, while that in the Mallinckrodt group decreased by 6% at H40. No significant change was observed in internal diameter in the Parker group, even when cuff pressure was increased. The internal diameter in the Portex group was the smallest at all cuff pressures in hot water. When the nasotracheal intubation tubes selected were placed in a simulated trachea and cuff pressure increased, internal diameter in the Portex and Mallinckrodt groups decreased.
Related Concept Videos
Pressure Relationships in Thoracic Cavity
Breathing Mechanisms
Both intra-alveolar and intrapleural pressures rely on specific lung properties. The ability to breathe—allowing air to enter the lungs...
Tracheostomy: Procedure and Tubes
Tracheostomy tubes can be made of semiflexible plastic (polyurethane or silicone), rigid plastic, or metal, and they come in...
Trachea
Anatomical Features:
Location: About half of the trachea is situated in the neck, anterior to the esophagus, and extends from the larynx (at the level of...
Endotracheal Intubation I: Procedure
The ET tube comprises various components, including a standard adaptor to attach a bag-valve-mask (BVM) or ventilator, a cuff, a pilot balloon, and radiopaque markings along its length to measure the insertion distance. The tube sizes...
Oxygen Delivering System III: Tracheostomy and T-piece
Tracheostomy
A tracheostomy is a surgically created opening (stoma) in the anterior part of the trachea. It is used to establish a patient airway, bypass an upper airway obstruction, simplify the removal of secretions, permit long-term...

