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Updated: Mar 24, 2026

A Rapid and Specific Microplate Assay for the Determination of Intra- and Extracellular Ascorbate in Cultured Cells
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[(11)C]Ascorbic and [(11)C]dehydroascorbic acid, an endogenous redox pair for sensing reactive oxygen species using

V N Carroll1, C Truillet, B Shen

  • 1Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California 94107, USA. David.M.Wilson@ucsf.edu.

Chemical Communications (Cambridge, England)
|March 11, 2016
PubMed
Summary

We developed radiolabeled vitamin C forms, [(11)C]ascorbic acid and [(11)C]dehydroascorbic acid, for detecting reactive oxygen species (ROS). This enables in vivo ROS detection using positron emission tomography (PET).

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