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Surgical options for the management of severe functional constipation in children
Richard J Wood1, Desale Yacob, Marc A Levitt
1aCenter for Colorectal and Pelvic Reconstruction, Pediatric Surgery, Nationwide Children's Hospital bDivision of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Nationwide Children's Hospital, Columbus, Ohio, USA.
Insights
Pediatric constipation often requires specialized interventions. This review highlights the limited evidence for surgical approaches in severe pediatric constipation and calls for standardized, prospective studies with validated outcomes.
Area of Science:
- Pediatric Surgery
- Gastroenterology
- Clinical Evidence Review
Background:
- Constipation is a prevalent pediatric issue with varied severity and management strategies.
- Most pediatric functional constipation cases resolve with conservative treatment, avoiding specialized testing or surgery.
- Intractable constipation, particularly with fecal soiling, necessitates specialized evaluation, including motility testing, for medical and surgical planning.
Purpose of the Study:
- To review existing literature on surgical interventions for severe pediatric constipation.
- To assess the quality and evidence levels of studies on surgical approaches.
- To evaluate the use of objective outcome measures in surgical treatment studies.
Main Methods:
- Literature review of publications concerning surgical approaches for severe constipation in children.
- Assessment of the quality and levels of evidence within the reviewed studies.
- Analysis of the application of objective measures for determining treatment outcomes.
Main Results:
- Limited recent studies evaluate surgical indications or treatments for functional constipation.
- Existing systematic reviews predominantly analyze older studies, with most evidence being Level 4 or 5.
- A standardized definition for 'failed medical management,' a common surgical indication, is lacking.
- Many proposed surgical procedures lack robust outcome data.
Conclusions:
- There is a critical need for protocolized, prospective studies on surgical evaluation and treatment of pediatric constipation.
- Validated outcome measures are essential for advancing the evidence base in this field.
- The described center's protocol for surgical evaluation and treatment is presented.
Purpose Of Review:
Constipation is a very common problem in pediatrics with both the severity of presentations and treatments varying across a broad spectrum. The majority of children with functional constipation are managed successfully without the need for specialized testing and surgical intervention. Those who present with intractable constipation, with or without fecal soiling, require referrals for motility testing that helps determine both medical and surgical management, and interventions. The literature was reviewed for publications on surgical approaches to children with severe constipation, including assessing the quality and levels of evidence and the use of objective measures to determine outcomes.
Recent Findings:
There is very little in the way of recent studies evaluating surgical indications or treatment approaches for functional constipation, apart from one systematic review and one recent expert review. Although the systematic review was published in the last year, most of the studies it analyzes are older. The vast majority of studies comprise level 4 and 5 evidence.
Summary:
The indication for most surgical procedures is 'failed' medical management, yet no standardized definition for this exists. Many surgical procedures are proposed with little evidence to show outcomes. We recommend that the surgical evaluation and treatment of children with constipation needs to be protocolized and studied in a prospective manner using validated outcomes measures. Our center's current protocol is described.
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