Related Experiment Video
Updated: Mar 24, 2026

Implementation of Minimally Invasive Brain Tumor Resection in Rodents for High Viability Tissue Collection
Published on: May 9, 2022
[Two Surgical Techniques for Metastatic Brain Tumors:Minimum Resection and Removal with Safety Margin]
Yoko Nakasu1, Koichi Mitsuya, Nakamasa Hayashi
1Division of Neurosurgery, Shizuoka Cancer Center.
Abstract:
Successful resection of cerebral metastases is based on good basic neurosurgical techniques, in conjunction with technologies for tumor localization. A clear understanding about the border zone pathology of metastatic lesions leads to two different techniques for safe and effective tumor removal. There is no capsule or pseudocapsule around the metastatic brain tumors. The border zone is widely heterogeneous, especially in lesions after stereotactic irradiation. Resection can be performed in a circumferential and en bloc fashion with sufficient safety margin of the normal brain in non-eloquent area. However, enucleation should be done without surrounding brain damage in and near eloquent areas.

