Related Experiment Video
Updated: Mar 24, 2026

In Vivo Confocal Microscopy in the Diagnosis and Management of Dry Eye: A Focus on Imaging Protocols and Interpretation
Published on: November 11, 2025
[Evaluation of Iris Morphology Viewed through Stromal Edematous Corneas by Infrared Camera]
Background:
We reported that the application of infrared camera enables us to observe iris morphology in Peters' anomaly through edematous corneas.
Purpose:
To observe the iris morphology in bullous keratopathy or failure grafts with an infrared camera.
Subjects And Methods:
Eleven bullous keratopathy or failure grafts subjects (6 men and 5 women, mean age ± SD; 72.7 ± 13.0 years old) were enrolled in this study. The iris morphology was observed by applying visible light mode and near infrared light mode of infrared camera (MeibomPen). The detectability of pupil shapes, iris patterns and presence of iridectomy was evaluated.
Results:
Infrared mode observation enabled us to detect the pupil shapes in 11 out of 11 cases, iris patterns in 3 out of 11 cases, and presence of iridetomy in 9 out of 11 cases although visible light mode observation could not detect any iris morphological changes.
Conclusion:
Applying infrared optics was valuable for observation of the iris morphology through stromal edematous corneas.

