Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Vaccinations

Vaccinations

Vaccines

Vaccines

Vaccines are among the most effective tools in preventive medicine, designed to prepare the immune system to recognize and combat infectious agents. By introducing antigens—substances that the immune system identifies as foreign—vaccines stimulate an adaptive immune response that leads to immunological memory. This immunological memory enables the body to mount a faster and more effective response upon future exposures to the actual pathogen.Vaccines can be categorized based on the...

Teratogenicity

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...

Development of Immunocompetence

Development of Immunocompetence

The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...

Cancer Vaccines

Cancer Vaccines

Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...

Transcytosis of IgG

Transcytosis of IgG

Transcytosis is the process in which molecules are internalized by endocytosis, transported across the cell, and released through exocytosis from the opposite end of the cell. Molecules such as insulin, immunoglobulins, and certain nutrients are transferred through the recycling endosomes by recycling and transcytosis.
IgG molecules from a mother undergo transcytosis starting around 13 weeks of gestation. The amount of IgG transferred and entering the fetal blood circulation increases with...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Variation in Postdischarge Opioid Prescribing After Childbirth and Associated Procedures.

Obstetrics and gynecology·2026

Same author

Can theory-driven implementation interventions help clinician champions promote opioid stewardship after childbirth? Protocol for a pragmatic implementation study.

Frontiers in global women's health·2025

Same author

Development of an implementation intervention to promote adoption of the COMFORT clinical practice guideline for peripartum pain management: a qualitative study.

Implementation science communications·2025

Same author

Intrapartum Electronic Cigarette Use and Birth Outcomes: Evidence from a Population-Based Study.

International journal of environmental research and public health·2024

Same author

Implementation and Clinical Impact of a Guideline for Standardized, Evidence-Based Induction of Labor.

American journal of perinatology·2024

Same author

Drivers of variation in postpartum opioid prescribing across hospitals participating in a statewide maternity care quality collaborative.

Birth (Berkeley, Calif.)·2023

Same journal

Clinical Nuances of Preterm Prelabor Rupture of Membranes: A Literature Review.

Obstetrical & gynecological survey·2026

Same journal

A New Perspective on Endometriosis: How Gut and Reproductive Tract Microbiota Influence Disease Progression?

Obstetrical & gynecological survey·2026

Same journal

Sentinel Lymph Node Biopsy for Gynecologic Cancers.

Obstetrical & gynecological survey·2026

Same journal

Amniotic Fluid Embolism: A Silent Threat to Maternal Life- An Up-to-Date Comprehensive Review of the Pathophysiology, Diagnosis, and Outcome.

Obstetrical & gynecological survey·2026

Same journal

A System Review of Pathophysiology, Diagnosis, and Clinical Management of Intrauterine Adhesions.

Obstetrical & gynecological survey·2026

Same journal

Atrial Fibrillation and Atrial Flutter in Pregnancy: Epidemiology, Pathophysiology, and Management.

Obstetrical & gynecological survey·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Mar 24, 2026

Intranasal Immunization and Milk Collection in Studies of Maternal Immunization in New Zealand White Rabbits Oryctolagus cuniculus

Intranasal Immunization and Milk Collection in Studies of Maternal Immunization in New Zealand White Rabbits Oryctolagus cuniculus

Published on: July 31, 2021

Vaccination During Pregnancy.

Michelle H Moniz¹, Richard H Beigi²

¹Assistant Professor, Department of Obstetrics and Gynecology, Institute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor, MI.

Obstetrical & Gynecological Survey

|March 19, 2016

Summary

This summary is machine-generated.

Active immunization during pregnancy offers significant benefits for both mothers and newborns by reducing infections. This review outlines current vaccination guidelines and implementation strategies for maternal immunization programs.

More Related Videos

Induction of Maternal Immune Activation in Mice at Mid-gestation Stage with Viral Mimic PolyI:C

Induction of Maternal Immune Activation in Mice at Mid-gestation Stage with Viral Mimic PolyI:C

Published on: March 25, 2016

Ex vivo Culture of Human Placental Explants for the Study of Viral Transmission Across the Maternal-Fetal Interface

Ex vivo Culture of Human Placental Explants for the Study of Viral Transmission Across the Maternal-Fetal Interface

Published on: December 30, 2025

Related Experiment Videos

Last Updated: Mar 24, 2026

Intranasal Immunization and Milk Collection in Studies of Maternal Immunization in New Zealand White Rabbits Oryctolagus cuniculus

Intranasal Immunization and Milk Collection in Studies of Maternal Immunization in New Zealand White Rabbits Oryctolagus cuniculus

Published on: July 31, 2021

Induction of Maternal Immune Activation in Mice at Mid-gestation Stage with Viral Mimic PolyI:C

Induction of Maternal Immune Activation in Mice at Mid-gestation Stage with Viral Mimic PolyI:C

Published on: March 25, 2016

Ex vivo Culture of Human Placental Explants for the Study of Viral Transmission Across the Maternal-Fetal Interface

Ex vivo Culture of Human Placental Explants for the Study of Viral Transmission Across the Maternal-Fetal Interface

Published on: December 30, 2025

Area of Science:

Immunology
Public Health
Obstetrics

Background:

Maternal immunization is a key strategy to protect pregnant women and infants from infectious diseases.
Implementing vaccination during pregnancy requires evidence-based clinical guidelines and public health initiatives.

Observation:

This review synthesizes data from clinical trials, observational studies, and meta-analyses.
Recommendations from major health organizations were analyzed to inform current practices.

Findings:

Current clinical guidelines support vaccination during pregnancy for maternal and neonatal health.
Effective implementation strategies are crucial for maximizing vaccine uptake and impact.

Implications:

Strengthening maternal immunization programs can significantly decrease infectious disease burden in mothers and infants.
Further research is needed to optimize maternal immunization schedules and expand vaccine accessibility.