The Bidirectional Associations Between Psychotic Experiences and DSM-IV Mental Disorders

John J McGrath1, Sukanta Saha1, Ali Al-Hamzawi1

  • 1From the Queensland Centre for Mental Health Research, Park Centre for Mental Health, Wacol, Australia; the Discipline of Psychiatry and the Queensland Brain Institute, University of Queensland, St. Lucia, Australia; the College of Medicine, Al-Qadisiya University, Diwania Governorate, Iraq; the Department and Institute of Psychiatry, University of São Paulo Medical School, São Paulo, Brazil; the Department of Epidemiologic and Psychosocial Research, National Institute of Psychiatry Ramon de la Fuente, Mexico City; the Department of Psychiatry, Stony Brook University School of Medicine, Stony Brook, N.Y.; the Centre for Mental Health, University of Melbourne, Melbourne, Australia; the Chronic Diseases Research Center (CEDOC) and the Department of Mental Health, Faculdade de Ciências Médicas, Universidade Nova de Lisboa, Lisbon, Portugal; the Department of Health Care Policy, Harvard University, Boston; the Department of Psychiatry, University Hospital Gasthuisberg, Katholieke Universiteit Leuven, Leuven, Belgium; the Institute for Development, Research, Advocacy, and Applied Care (IDRAAC), Beirut, Lebanon; the National School of Public Health, Management, and Professional Development, Bucharest, Romania; IRCCS St. John of God Clinical Research Centre, IRCCS Centro S. Giovanni di Dio Fatebenefratelli, Brescia, Italy; the Department of Psychiatry, University College Hospital, Ibadan, Nigeria; Parc Sanitari Sant Joan de Deïu, CIBERSAM, Sant Boi de Llobregat, Barcelona, Spain; Trimbos-Instituut, Netherlands Institute of Mental Health and Addiction, Utrecht; the Shenzhen Insitute of Mental Health and Shenzhen Kanging Hospital, Shenzhen, China; Ecole des Hautes Etudes en Santé Publique (EHESP), Paris Descartes University, Paris; the Department of Psychological Medicine, Dunedin School of Medicine, University of Otago, New Zealand; IMIB-Arrixaca, CIBERESP-Murcia, Subdirección General de Salud Mental y Asistencia Psiquiátrica, Servicio Murciano de Salud, El Palmar (Murcia), Spain; Colegio Mayor de Cundinamarca University, Bogotá, Colombia; and the Department of Psychiatry, Virginia Commonwealth University, Richmond.

Summary

Psychotic experiences increase the risk of developing mental disorders. However, most mental disorders also elevate the risk of later psychotic experiences, suggesting a complex bidirectional relationship.

Related Concept Videos

Diagnostic and Statistical Manual of Mental Disorders (DSM)01:27

Diagnostic and Statistical Manual of Mental Disorders (DSM)

The Diagnostic and Statistical Manual of Mental Disorders (DSM) serves as the primary classification system for mental health disorders, providing standardized diagnostic criteria for clinicians and researchers. First published by the American Psychiatric Association (APA) in 1952, the DSM has undergone several revisions to reflect evolving psychiatric understanding. The fifth edition, DSM-5, released in 2013, introduced key updates that expanded diagnostic categories and modified diagnostic...
1.6K
Dissociative Identity Disorder01:30

Dissociative Identity Disorder

Dissociative Identity Disorder (DID), previously termed multiple personality disorder, is a complex psychological condition characterized by the presence of two or more distinct identities or personality states. Each identity exhibits unique patterns of behavior, voice, and mannerisms and may possess separate memories and emotional responses. The alternating control between identities can result in memory gaps and challenges in recalling daily activities, often exacerbating the individual's...
1.7K
Psychosis and Antipsychotic Drugs: Overview01:28

Psychosis and Antipsychotic Drugs: Overview

The term "psychosis" refers to a spectrum of mental disorders characterized by abnormal thoughts, perceptions, and behaviors. It can manifest as mood disorders, dementia, delirium with psychotic features, substance-induced psychosis with psychotic features, brief psychotic disorder, delusional disorder, schizoaffective disorder, and schizophrenia. Among all these disorders, schizophrenia is the most common psychotic disorder, affecting 1% of the worldwide population. Psychotic...
1.1K
Psychological and Sociocultural Causes of Schizophrenia01:29

Psychological and Sociocultural Causes of Schizophrenia

Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
810
Positive Symptoms Schizophrenia: Hallucinations and Delusions01:26

Positive Symptoms Schizophrenia: Hallucinations and Delusions

Schizophrenia is a complex psychiatric disorder characterized by a range of symptoms that significantly impact cognition, behavior, and emotional regulation. Among these, the positive symptoms stand out as they involve the addition or exaggeration of normal mental functions, deviating markedly from typical behavior and perception. Hallucinations and delusions are prominent positive symptoms, each profoundly affecting the individual's experience of reality.
Hallucinations
Hallucinations in...
927
Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders01:27

Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders

Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within...
2.4K