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Transient Constrictive Pericarditis: Current Diagnostic and Therapeutic Strategies
James Gentry1, Allan L Klein1, Christine L Jellis2
1Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, Desk J1-5, 9500 Euclid Avenue, Cleveland, OH, 44195, USA.
Current Cardiology Reports
|March 21, 2016
Summary
Transient constrictive pericarditis, characterized by inflammation, is a distinct subtype of constrictive pericarditis. Early diagnosis via imaging and anti-inflammatory treatment can improve outcomes and prevent chronic constriction.
Area of Science:
- Cardiology
- Internal Medicine
- Medical Imaging
Background:
- Transient constrictive pericarditis is an emerging subtype of constrictive pericarditis.
- Its pathophysiology involves impaired pericardial distensibility due to acute/subacute inflammation, differing from chronic fibrotic/calcific types.
- Patients may exhibit concurrent pericarditis and constrictive physiology.
Purpose of the Study:
- To highlight the distinct characteristics of transient constrictive pericarditis.
- To emphasize the role of non-invasive multimodality imaging in diagnosis.
- To discuss therapeutic strategies for managing transient constrictive pericarditis.
Main Methods:
- Utilized echocardiography for initial evaluation of dynamic constriction.
- Employed cardiac magnetic resonance imaging for functional assessment and detection of pericardial inflammation/edema.
- Reviewed clinical presentations and treatment outcomes.
Main Results:
- Transient constrictive pericarditis presents with features of both pericarditis and constriction.
- Echocardiography and cardiac magnetic resonance imaging are key diagnostic tools.
- The condition can resolve spontaneously or with anti-inflammatory therapy.
Conclusions:
- Transient constrictive pericarditis requires specific diagnostic and therapeutic approaches.
- Prompt diagnosis and anti-inflammatory treatment can lead to resolution and prevent progression to chronic constrictive pericarditis.
- Non-steroidal anti-inflammatory drugs are first-line therapy, with other agents considered for refractory cases.
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