Self-Assembled Nanospheres for Encapsulation and Aerosolization of Rifampicin
Aline A Ishikawa1, Jesus V Salazar2, Magaly Salinas3
1School of Pharmaceutical Sciences of Ribeirão Preto, Ribeirao Preto, SP, Brazil; Department of Chemistry, Clemson University, Clemson, SC 29634, USA.
Abstract:
Rifampicin (RIF) is a benchmark drug for treatment of tuberculosis, but poor bioavailability, prolonged treatment, and pill burden have been linked to therapeutic failure and the development of multidrug resistant strains. To overcome these limitations, this study investigated a method of rifampicin nanoencapsulation and aerosol delivery using a commercial, hand-held nebulizer modified with a nitrogen stream.
More Related Videos
06:57Rapid, Scalable Assembly and Loading of Bioactive Proteins and Immunostimulants into Diverse Synthetic Nanocarriers Via Flash Nanoprecipitation
Published on: August 11, 2018
10:12Flash NanoPrecipitation for the Encapsulation of Hydrophobic and Hydrophilic Compounds in Polymeric Nanoparticles
Published on: January 7, 2019