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Uropharmacology: VII. Ganglionic stimulating and blocking agents
Urology
|April 1, 1978
Summary
This study classifies ganglionic stimulants and blockers, detailing their effects on the urinary bladder and urethra. While stimulants are investigational, certain blockers like mecamylamine are therapeutically relevant.
Area of Science:
- Pharmacology
- Urology
Background:
- Ganglionic stimulants and blockers represent a class of drugs with significant physiological effects.
- Their impact on the urinary system, specifically the bladder and urethra, warrants detailed examination.
Purpose of the Study:
- To classify various ganglionic stimulating and blocking agents.
- To discuss the pharmacologic effects of these agents on the urinary bladder and urethra.
Main Methods:
- Literature review and classification of known ganglionic drugs.
- Analysis of pharmacological data regarding their effects on urinary system components.
Main Results:
- Ganglionic stimulating drugs are currently limited to investigational use.
- Ganglionic blockers include numerous agents, with mecamylamine, pentolinium, and trimethaphan being officially recognized for therapeutic application.
Conclusions:
- A clear distinction exists between investigational ganglionic stimulants and therapeutically relevant ganglionic blockers.
- Understanding the specific effects of ganglionic blockers on the urinary tract is crucial for their clinical application.