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Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment
Published on: April 22, 2019
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MANDIBULAR SQUAMOUS CELL CARCINOMA IN A BOBCAT (LYNX RUFUS)
Summary
A bobcat (Lynx rufus) was diagnosed with oral squamous cell carcinoma of the mandible. This is the first reported case of this cancer in a bobcat, leading to euthanasia due to poor prognosis.
Area of Science:
- Veterinary Medicine
- Comparative Oncology
- Wildlife Health
Background:
- Oral squamous cell carcinoma (SCC) is a common malignancy in various animal species.
- Information on SCC in wild felids, such as bobcats (Lynx rufus), is limited.
- Early detection and understanding of risk factors are crucial for wildlife conservation and management.
Observation:
- A 23-year-old female bobcat presented with hypersalivation and a thickened, ulcerated right mandible.
- Physical examination revealed a missing right mandibular dental arcade and oral mucosal lesions.
- Skull radiographs and fine needle aspirate cytology suggested squamous cell carcinoma.
Findings:
- Necropsy confirmed oral squamous cell carcinoma originating from the mandible.
- The tumor's extensive nature and location contributed to the poor prognosis.
- This case represents the first documented instance of oral SCC in a bobcat.
Implications:
- This report highlights the potential for oral SCC in bobcats, contributing to the understanding of cancer in wild felids.
- Further research into the etiology and prevalence of SCC in bobcats may inform conservation strategies.
- This case underscores the importance of recognizing neoplastic conditions in wildlife populations.

