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Coats' Disease: Very Long-Term Outcome After Early Stage Conventional Treatment

Salvatore Perrone1, Alberto Rossetti1, Patrick Sportiello1

  • 1Department of Ophthalmology, University Hospital of Padua, Padua, Italy.

The Open Ophthalmology Journal
|March 26, 2016
PubMed

Insights

Conventional therapy for Coats

Area of Science:

  • Ophthalmology
  • Retinal Diseases

Background:

  • Coats' disease is a rare idiopathic retinal vascular anomaly.
  • Characterized by retinal telangiectasia and exudation.

Purpose of the Study:

  • To evaluate the long-term outcomes of conventional treatments for Coats' disease.
  • To assess the efficacy of argon laser photocoagulation and cryotherapy.

Main Methods:

  • Retrospective chart analysis of 13 patients diagnosed with Coats' disease.
  • Treatment modalities included argon laser photocoagulation and/or cryotherapy.
  • Mean follow-up period of 32.5 years.

Main Results:

  • Eyes with stage 2a disease (without foveal involvement) maintained or improved visual acuity (VA).
  • Eyes with stage 2b disease showed minimal VA deterioration.
  • Advanced complications like phthisis or neovascular glaucoma occurred in a minority of eyes with total retinal detachment.

Conclusions:

  • Conventional therapy offers sustained good visual acuity for stage 2a Coats' disease.
  • Treatment prevents progression to advanced stages in stage 2b Coats' disease over decades.
Abstract

Keywords:
Coats' diseaseexudative retinopathyneovascular glaucomaretinal detachmenttelangiectasia

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