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Updated: Mar 23, 2026

A New Straightforward Method for Lipophilicity logP Measurement using 19F NMR Spectroscopy
Published on: January 30, 2019
Parallel NMR spectroscopy with simultaneous detection of (1) H and (19) F nuclei
1Bruker BioSpin AG, Industriestrasse 26, CH-8117, Fällanden, Switzerland.
Abstract:
Recording NMR signals of several nuclear species simultaneously by using parallel receivers provides more information from a single measurement and at the same time increases the measurement sensitivity per unit time. Here we present a comprehensive series of the most frequently used NMR experiments modified for simultaneous direct detection of two of the most sensitive NMR nuclei - (1) H and (19) F. We hope that the presented material will stimulate interest in and further development of this technique.
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