Optical Coherence Tomography Angiography of Choroidal Neovascularization Secondary to Pathologic Myopia

To analyze the ability of optical coherence tomography angiography (OCT-A) to detect the presence of myopic choroidal neovascularization (CNV) and to describe structural features of myopic CNV on OCT-A.

Patients with CNV secondary to high myopia (>6 diopters and >26 mm axial length) underwent multimodal imaging, including multicolor imaging, fluorescein angiography, spectral-domain (SD)-OCT and OCT-A. The OCT-A features of CNV were analyzed and correlated with the angiography and SD-OCT findings.

On OCTA, the CNV appeared as a large hyperintense vascular anastomotic network at the edge of the lesion. On the basis of the OCT-A images and reports in the literature, we propose the following two terms for describing myopic CNV characteristics: 'interlacing' and 'tangled' vascular networks.

OCT-A is a very useful tool for the diagnosis and evaluation of CNV complicating high myopia; however, it does not appear to be sufficient when used alone and should be considered for use in combination with SD-OCT and conventional angiography.