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Updated: Mar 23, 2026

Non-invasive Optical Measurement of Cerebral Metabolism and Hemodynamics in Infants
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A 6-month-old Female with Fever and Increased Head Circumference

Collin C John, Ashley Jenkins, Hilary Morley

    The West Virginia Medical Journal
    |March 31, 2016
    PubMed

    Insights

    Methicillin-sensitive Staphylococcus aureus (MSSA) is a rare cause of brain abscesses in infants. This case highlights a MSSA brain abscess in a 6-month-old without typical risk factors, emphasizing the need for vigilance.

    Area of Science:

    • Pediatric Neurology
    • Infectious Diseases
    • Neurosurgery

    Background:

    • Brain abscesses in children are uncommon but serious, carrying risks of severe illness and death.
    • Staphylococcus aureus is an infrequent cause of pediatric intracranial abscesses, typically linked to trauma or surgery.

    Observation:

    • A 6-month-old infant presented with a large brain abscess.
    • The abscess was caused by methicillin-sensitive Staphylococcus aureus (MSSA).
    • No clear predisposing factors, such as trauma or neurosurgery, were identified.

    Findings:

    • The infant underwent percutaneous drainage and intravenous antibiotic therapy.
    • Initial recovery was observed, but long-term developmental outcomes remain uncertain.
    • This case underscores MSSA as a potential pathogen in pediatric brain abscesses even without typical risk factors.

    Implications:

    • Highlights the importance of considering MSSA in pediatric brain abscesses, irrespective of apparent risk factors.
    • Emphasizes the need for prompt diagnosis and multidisciplinary management, including surgical drainage and antibiotics.
    • Underscores the potential for significant neurological sequelae in pediatric brain abscess survivors.

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