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Updated: Mar 23, 2026

Influenza A Virus Studies in a Mouse Model of Infection
Published on: September 7, 2017
Studies of Influenza A/H1N1 A/Tomsk/13/2010 Virus Topology during Development of Infectious Process in Mammals
O V Potapova1, A V Kovner2, A G Anikina1
1Institute of Experimental and Clinical Medicine, Novosibirsk, Russia.
Abstract:
Influenza A/H1N1 A/Tomsk/13/2010 virus registered in Siberia in 2010 proved to be an extremely pathogenic strain. Dynamic study of the topology of this influenza virus strain in the lungs, liver, kidneys, lymph nodes, and great vessels of infected mice was carried out. Influenza A virus was detected by immunohistochemical methods in cells of different histogenesis in all the studied organs throughout the observation period (days 1-30 postinfection), which indicated effective replication and long persistence of influenza A/H1N1 A/Tomsk/13/2010 virus in mammalian cells.
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