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Related Experiment Video

Updated: Mar 23, 2026

Zika Virus Infectious Cell Culture System and the In Vitro Prophylactic Effect of Interferons

Zika Virus Infectious Cell Culture System and the In Vitro Prophylactic Effect of Interferons

Published on: August 23, 2016

Zika Virus.

Didier Musso¹, Duane J Gubler²

¹Unit of Emerging Infectious Diseases, Institut Louis Malardé, Tahiti, French Polynesia dmusso@ilm.pf duane.gubler@duke-nus.edu.sg.

Clinical Microbiology Reviews

|April 1, 2016

Summary

This summary is machine-generated.

Zika virus (ZIKV), an arbovirus, has emerged globally, causing mild illness until recent outbreaks linked to severe neurological issues and microcephaly. Its transmission by mosquitoes poses a significant risk in tropical urban areas.

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Vector Competence Analyses on Aedes aegypti Mosquitoes using Zika Virus

Vector Competence Analyses on Aedes aegypti Mosquitoes using Zika Virus

Published on: May 31, 2020

Area of Science:

Virology
Epidemiology
Public Health

Background:

Zika virus (ZIKV) is an arbovirus transmitted by mosquitoes, first isolated in Africa in the 1940s.
Human infections were initially sporadic but ZIKV has since emerged in the Pacific and Americas.
ZIKV infection typically causes mild illness but has been linked to severe neurological complications and microcephaly.

Purpose of the Study:

To review the epidemiology and clinical manifestations of Zika virus.
To discuss diagnostic challenges and the potential for future outbreaks.
To highlight the public health implications of ZIKV emergence.

Main Methods:

Literature review of ZIKV isolation, transmission, clinical cases, and diagnostics.
Analysis of ZIKV's adaptation to urban cycles and vector competence.
Assessment of ZIKV's association with neurological complications and congenital malformations.

Main Results:

ZIKV emerged in the Pacific and Americas, with outbreaks linked to severe neurological complications and microcephaly.
Clinical diagnosis is challenging due to nonspecific symptoms and cross-reactivity in serological tests.
ZIKV's adaptation to urban cycles suggests potential for widespread transmission in tropical areas.

Conclusions:

Zika virus poses a significant public health threat due to its potential for widespread emergence in urban centers.
Accurate diagnostics and vector control are crucial for managing ZIKV outbreaks.
Further research is needed to understand the full spectrum of ZIKV-related diseases and to develop effective interventions.