Related Experiment Video
Updated: Mar 23, 2026

Author Spotlight: Modeling an Aspect of Preeclampsia in Female Mice Using Hypoxic Human Placenta-Derived Small Extracellular Vesicles
Published on: January 26, 2024
Pre-eclampsia and Cardiovascular Disease Risk Assessment in Women
Malia S Q Murphy1, Graeme N Smith1
1Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada.
Insights
Pregnancy complications like pre-eclampsia significantly increase a woman's risk for premature cardiovascular disease (CVD). Early screening and risk factor identification in young women are crucial for preventing CVD.
Area of Science:
- Cardiology
- Obstetrics & Gynecology
- Preventive Medicine
Background:
- Cardiovascular disease (CVD) risk factors often emerge decades before symptoms, with early life factors significantly impacting premature CVD risk.
- Pregnancy complications, including pre-eclampsia (PE), gestational hypertension, and gestational diabetes mellitus, are recognized contributors to a woman's long-term cardiovascular risk.
- The substantial burden of CVD in women necessitates a focus on prevention and early risk assessment.
Purpose of the Study:
- To review risk factors in young women contributing to premature CVD.
- To highlight pre-eclampsia (PE) as a key marker for cardiovascular risk assessment in women.
- To discuss current screening practices for identifying and mitigating CVD risk in younger women.
Main Methods:
- Literature review of studies on cardiovascular risk factors in young women.
- Analysis of the association between pregnancy complications and long-term CVD risk.
- Examination of current cardiovascular screening guidelines and their applicability to younger women.
Main Results:
- Pregnancy-related complications like PE are significant indicators of future cardiovascular risk.
- Early identification of risk factors during and after pregnancy can inform preventive strategies.
- Current screening practices may not adequately address CVD risk in younger women.
Conclusions:
- Pre-eclampsia serves as a critical warning sign for future cardiovascular disease in women.
- Integrating obstetric history into cardiovascular risk assessments can improve early detection.
- Enhanced screening and prevention strategies are needed for young women to reduce premature CVD.
Abstract:
The underlying contributors of many cardiovascular events are often present decades before the onset of clinical symptoms, and the presence of risk factors in early life significantly influences risk of premature cardiovascular disease (CVD). The considerable burden of CVD in women and on health care resources necessitates an emphasis on prevention and early risk screening in women, before the development of the disease itself. The 2011 update to the American Heart Association's Effectiveness-Based Guidelines for the prevention of CVD acknowledges the contribution of the common pregnancy-related medical complications to a woman's cardiovascular risk, identifying pre-eclampsia (PE), gestational hypertension, and gestational diabetes mellitus as risk factors for heart disease and stroke. The aims of this review are to examine risk factors in young women and their role in the development of premature CVD, with particular attention paid to PE as a marker of a woman's cardiovascular risk. Current screening practices will be discussed, as will their influences on identifying and reducing cardiovascular risk and subsequent disease in younger women.
Related Concept Videos
Hypertension III: Clinical Manifestations and Diagnostic Studies
Coronary Artery Disease I: Introduction
Assessment of the Cardiovascular System I: Subjective Data
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
Mitral Valve Prolapse III: Nursing Management
Coronary Artery Disease IV: Preventive Measures
