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Piezogenic Pedal Papules with Mitral Valve Prolapse
Cihan Altin1, Ulku Askin2, Esin Gezmis3
1Department of Cardiology, Faculty of Medicine, University of Baskent, İzmir, Turkey.
Piezogenic pedal papules (PPP), skin lesions on the feet, may indicate underlying connective tissue abnormalities and cardiac conditions like mitral valve prolapse (MVP). Further cardiac evaluation is recommended for patients with PPP.
Area of Science:
- Dermatology
- Cardiology
- Genetics
Background:
- Piezogenic pedal papules (PPP) are common skin findings on the feet.
- These papules are herniations of subcutaneous fat into the dermis.
- PPP have been anecdotally associated with connective tissue disorders.
Purpose of the Study:
- To investigate the potential association between Piezogenic pedal papules (PPP) and Mitral Valve Prolapse (MVP).
- To highlight the importance of cardiac evaluation in patients presenting with PPP.
- To report cases of concurrent PPP and MVP, as no prior literature exists.
Main Methods:
- Case report presentation.
- Clinical examination of patients with PPP.
- Cardiac assessment including echocardiography for MVP diagnosis.
Main Results:
- Piezogenic pedal papules (PPP) are characterized as papules and nodules on the feet.
- Mitral valve prolapse (MVP) involves myxomatous degeneration of the mitral valve.
- The study reports cases suggesting a potential link between PPP and MVP.
Conclusions:
- Piezogenic pedal papules (PPP) may serve as a cutaneous marker for systemic connective tissue abnormalities.
- Cardiac evaluation, particularly for Mitral Valve Prolapse (MVP), is warranted in patients with PPP.
- This report highlights a previously undocumented association between PPP and MVP.
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