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Nose and Nasal Cavity01:24

Nose and Nasal Cavity

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The nose is composed of an observable exterior segment (external nose) and an internal segment within the skull known as the nasal cavity (internal nose). The external nose, visible on the face, consists of a framework of bone and hyaline cartilage enveloped in skin and muscle and lined with a mucous membrane. This structure is supported by the frontal bone, nasal bones, and maxillary bone and is supplemented by a cartilaginous framework comprising the septal nasal cartilage, lateral nasal...
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The lateral view of the cranium is dominated by temporal, sphenoid, and ethmoid bones.
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
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The upper respiratory tract plays a vital role in the respiratory system, comprising several structures that facilitate air intake and prepare air for the lungs. It also serves as the first line of defense against pathogens and particles. This tract includes the nose and nasal cavity, the oral cavity, the paranasal sinuses, and the pharynx, each with specific functions and features.
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Related Experiment Video

Updated: Mar 22, 2026

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
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[Sinunasal Tumors].

C Arens

    Laryngo- Rhino- Otologie
    |April 9, 2016
    PubMed
    Summary

    Sinunasal tumors are rare and diverse, requiring individualized surgical approaches. Despite minor survival improvements for sinunasal malignancies (SNM), outcomes remain suboptimal, necessitating advanced multimodal treatments.

    Area of Science:

    • Otolaryngology
    • Head and Neck Surgery
    • Oncology

    Background:

    • Sinunasal tumors are rare, heterogeneous lesions affecting the nose, sinuses, and skull base.
    • These tumors exhibit diverse biological activities and clinical behaviors, necessitating tailored treatment strategies.
    • Current treatment outcomes for sinunasal malignancies (SNM) show only modest improvements in overall survival.

    Purpose of the Study:

    • To highlight the need for more effective local and systemic treatments for sinunasal tumors.
    • To explore novel multimodal treatment strategies for improving patient quality of life and survival.

    Main Methods:

    • Review of current treatment approaches for sinunasal tumors.
    • Analysis of recent advancements in surgical techniques, chemoradiation, and antibody therapies.

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    Main Results:

    • Despite advancements, overall survival for sinunasal malignancies remains moderate to low.
    • Multimodal strategies integrating new surgical concepts, chemoradiation, and antibody treatments show promise.

    Conclusions:

    • There is a critical need for enhanced local and systemic treatment modalities for sinunasal tumors.
    • Innovative multimodal treatment strategies offer potential for improved quality of life and survival in patients with sinunasal tumors.