Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

142
Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin,...
142
Allergic Reactions02:06

Allergic Reactions

33.4K
Overview
33.4K
Drugs Used in Upper Respiratory Disorders: Overview01:16

Drugs Used in Upper Respiratory Disorders: Overview

983
Upper respiratory tract disorders, including viral infections and allergic rhinitis, cause significant discomfort and disrupt daily life. Managing these conditions involves a variety of drugs, such as antihistamines, intranasal steroids, decongestants, antitussives, expectorants, and mucolytics. Specific examples of drugs in each category are provided.
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
983
Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

3.3K
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
3.3K
Allergic Drug Reactions01:27

Allergic Drug Reactions

1.6K
Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
1.6K
Upper Respiratory Drugs: Decongestants01:27

Upper Respiratory Drugs: Decongestants

1.3K
Decongestants are a class of medications used primarily to alleviate nasal congestion, a common symptom resulting from allergies, colds, sinusitis, and other upper respiratory tract infections. These drugs work by activating α-adrenergic receptors, constricting small blood vessels in the nasal membranes. This action results in the opening of clogged nasal passages, thereby facilitating sinus drainage and relieving congestion.
Most decongestants are readily available over-the-counter in...
1.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Long Road of Long COVID: Specific Considerations for the Allergist/Immunologist.

The journal of allergy and clinical immunology. In practice·2023
Same author

A concept for integrated care pathways for atopic dermatitis-A GA<sup>2</sup> LEN ADCARE initiative.

Clinical and translational allergy·2023
Same author

Evaluation of patient-reported outcome measures for on-demand treatment of hereditary angioedema attacks and design of KONFIDENT, a phase 3 trial of sebetralstat.

Clinical and translational allergy·2023
Same author

Clinical severity classes in COVID-19 pneumonia have distinct immunological profiles, facilitating risk stratification by machine learning.

Frontiers in immunology·2023
Same author

Efficacy of Biologics in Patients with Allergic Severe Asthma, Overall and by Blood Eosinophil Count: A Literature Review.

Advances in therapy·2023
Same author

An updated review of pediatric autoimmune neuropsychiatric disorders associated with Streptococcus/pediatric acute-onset neuropsychiatric syndrome, also known as idiopathic autoimmune encephalitis: What the allergist should know.

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology·2023
Same journal

Anaphylaxis: State-of-the-Art.

Immunology and allergy clinics of North America·2026
Same journal

Upending Impending Doom.

Immunology and allergy clinics of North America·2026
Same journal

Mast Cell Activation Syndrome and Mimickers.

Immunology and allergy clinics of North America·2026
Same journal

Hereditary Alpha-Tryptasemia (HαT) as a Risk Modifier for Severe Anaphylaxis.

Immunology and allergy clinics of North America·2026
Same journal

Emerging Therapies for Anaphylaxis.

Immunology and allergy clinics of North America·2026
Same journal

Novel Epinephrine Delivery Devices.

Immunology and allergy clinics of North America·2026
See all related articles

Related Experiment Video

Updated: Mar 22, 2026

Author Spotlight: Advancing Allergic Rhinitis Research with Multicolor Immunofluorescence
06:08

Author Spotlight: Advancing Allergic Rhinitis Research with Multicolor Immunofluorescence

Published on: September 22, 2023

2.8K

Nonallergic Rhinitis: Diagnosis.

Justin Greiwe1, Jonathan A Bernstein1

  • 1Bernstein Allergy Group, 8444 Winton Rd, Cincinnati, OH 45231, USA; Division of Allergy, Immunology and Rheumatology, University of Cincinnati, 231 Albert Sabin Way, Cincinnati, OH 45267, USA.

Immunology and Allergy Clinics of North America
|April 17, 2016
PubMed
Summary
This summary is machine-generated.

Nonallergic rhinitis (NAR) is a common condition impacting millions, yet it is poorly understood and challenging to treat effectively. Further research into its mechanisms and prevalence is crucial for improved patient outcomes.

Keywords:
ClassificationDifferential diagnosisNonallergic rhinitisProvocationSubtypesSymptomsTriggers

More Related Videos

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
08:47

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

Published on: March 3, 2023

3.1K
Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis
03:40

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis

Published on: December 20, 2024

1.7K

Related Experiment Videos

Last Updated: Mar 22, 2026

Author Spotlight: Advancing Allergic Rhinitis Research with Multicolor Immunofluorescence
06:08

Author Spotlight: Advancing Allergic Rhinitis Research with Multicolor Immunofluorescence

Published on: September 22, 2023

2.8K
Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
08:47

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

Published on: March 3, 2023

3.1K
Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis
03:40

Acupoint Catgut Embedding Therapy in Traditional Chinese Medicine for Managing Allergic Rhinitis

Published on: December 20, 2024

1.7K

Area of Science:

  • Allergy and Immunology
  • Otolaryngology
  • Epidemiology

Background:

  • Nonallergic rhinitis (NAR) is a prevalent condition affecting millions, significantly impacting patient quality of life.
  • Despite its commonality, NAR is frequently underdiagnosed and inadequately managed by healthcare providers, leading to suboptimal clinical results.
  • Current understanding of NAR's underlying mechanisms is limited and evolving, complicating diagnosis and treatment strategies.

Purpose of the Study:

  • To highlight the challenges in diagnosing and managing nonallergic rhinitis.
  • To emphasize the need for a deeper understanding of NAR's underlying mechanisms.
  • To underscore the necessity of epidemiologic studies to define NAR's prevalence and economic impact.

Main Methods:

  • Review of current clinical practices and understanding of nonallergic rhinitis.
  • Analysis of the diagnostic challenges associated with NAR.
  • Identification of gaps in research regarding NAR mechanisms and epidemiology.

Main Results:

  • Nonallergic rhinitis is often poorly managed, resulting in poor clinical outcomes.
  • Accurate diagnosis of NAR requires a sophisticated understanding of its complex and evolving mechanisms.
  • There is a significant need for more comprehensive epidemiologic data on NAR.

Conclusions:

  • Nonallergic rhinitis requires more effective management strategies.
  • Further research is essential to elucidate the specific mechanisms driving NAR.
  • Epidemiologic studies are needed to justify research funding for NAR and develop targeted treatments.