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Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

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Related Experiment Video

Updated: Mar 22, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

Evaluating glaucoma damage: emerging imaging technologies.

Tigran Kostanyan¹, Gadi Wollstein¹, Joel S Schuman²

¹Department of Ophthalmology, UPMC Eye Center, Eye and Ear Institute, Ophthalmology and Visual Science Research Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

Expert Review of Ophthalmology

|April 19, 2016

Summary

This summary is machine-generated.

New ocular imaging technologies offer improved detection of glaucoma damage. These advancements in speed, depth, and multimodal capabilities promise earlier and more reliable glaucoma diagnosis.

Keywords:

Adaptive Optics Glaucoma OCT Aqueous Humor Outflow OCT Blood Flow Phase Sensitive OCT Polarization Sensitive OCT Spectral Domain OCT Swept Source OCT

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Last Updated: Mar 22, 2026

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

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Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

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In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

Published on: July 24, 2020

Area of Science:

Ophthalmology
Medical Imaging
Vision Science

Background:

Glaucoma diagnosis relies on estimating structural and functional damage.
Ocular imaging is a key tool in clinical practice and vision research for glaucoma.
Existing imaging methods face limitations in early and reliable detection.

Purpose of the Study:

To review novel ocular imaging modalities for glaucoma diagnosis.
To highlight advancements in imaging technology relevant to glaucoma detection.
To discuss the potential of new tools for earlier and more reliable glaucoma diagnosis.

Main Methods:

Review of recent literature on ocular imaging technologies.
Focus on advancements in scanning speed, penetration depth, and image registration.
Examination of multimodal imaging devices for glaucoma assessment.

Main Results:

Technological evolution enhances the reliability of glaucoma pathology detection.
Increased scanning speed and penetration depth improve imaging capabilities.
Multimodal devices offer comprehensive assessment for earlier diagnosis.

Conclusions:

New ocular imaging modalities are crucial for advancing glaucoma diagnosis.
Continued innovation in imaging technology promises earlier and more accurate detection of glaucoma.
These advancements are vital for improving patient outcomes in glaucoma management.