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Related Concept Videos

Diabetes Mellitus: Overview and Type I Subtype01:22

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Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
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Diabetes Mellitus: Type 2 and Gestational01:22

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Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
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Pathophysiology of Diabetes01:20

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Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
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Diabetes: Management and Pharmacotherapy01:15

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The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
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Diabetes: Symptoms, Diagnosis, and Complications01:15

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For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
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Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
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Updated: Mar 22, 2026

A Zebrafish Model of Diabetes Mellitus and Metabolic Memory
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Diabetes Mellitus Review.

Meg Blair

    Urologic Nursing
    |April 21, 2016
    PubMed
    Summary
    This summary is machine-generated.

    This review covers type 2 diabetes (T2D), a common condition of impaired glucose regulation. It details T2D

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    Area of Science:

    • Endocrinology
    • Metabolic Disorders
    • Diabetes Research

    Background:

    • Diabetes mellitus involves hyperglycemia due to insulin resistance, inadequate insulin secretion, or excess glucagon.
    • Type 1 diabetes (T1D) is autoimmune, destroying pancreatic beta-cells.
    • Type 2 diabetes (T2D) is more prevalent, characterized by impaired glucose regulation from beta-cell dysfunction and insulin resistance.

    Purpose of the Study:

    • To review the fundamental science of type 2 diabetes (T2D).
    • To explore the complications associated with T2D.
    • To discuss current, evidence-based treatment guidelines for T2D management.

    Main Methods:

    • Literature review of basic science principles in T2D.
    • Analysis of T2D pathophysiology and progression.
    • Synthesis of recent clinical guidelines for T2D treatment.

    Main Results:

    • T2D results from a combination of insulin resistance and pancreatic beta-cell dysfunction.
    • Hyperglycemia is a key indicator of diabetes mellitus.
    • Complications of T2D are diverse and impact multiple organ systems.

    Conclusions:

    • Understanding T2D's basic science is crucial for effective management.
    • Recent treatment guidelines emphasize a multifaceted approach to T2D care.
    • Continued research is vital for improving T2D outcomes.