Comparison of Corneal Diameter and Anterior Chamber Depth Measurements Using 4 Different Devices

To evaluate the reliability and validity of anterior chamber depth (ACD) and corneal diameter [white-to-white (WTW) distance] measurements with 4 devices as well as applicability of these values in predicting the anterior chamber angle diameter evaluated by optical coherence tomography for implantation of lenses in the anterior chamber.

In this prospective randomized case series, we measured ACD and WTW distance in one eye of 40 healthy subjects with Pentacam HR, IOL Master 500, LenStar 900, and Visante OCT.

When comparing WTW distance with anterior chamber angle diameter measured by Visante OCT coefficient of repeatability and limits of agreement ranges were 0.5 and 1.1 mm for IOL Master, 0.5 and 1.1 mm for Pentacam HR, and 0.6 and 1.1 mm for LenStar (P < 0.05 in all cases), respectively. Coefficient of repeatability and limits of agreement ranges were 0.3 and 0.6 mm for IOL Master, 0.3 and 0.5 mm for Pentacam HR, and 0.3 and 0.6 mm for LenStar, respectively, compared with ACD measured by Visante OCT; however, P was not significant in any of the cases. P value was also not significant when comparing IOL Master, LenStar, and Pentacam in terms of ACD and WTW distance with each other.

Unlike previous groups analyzing the ACD and WTW distance we found no significant difference between the measurements by different automatic devices. We consequently expect no difference in clinical outcome when measurements for WTW distance or ACD are performed with any of the devices listed above.