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Updated: Mar 22, 2026

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
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Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents

Published on: May 28, 2014

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Pyridine Based Antitumour Compounds Acting at the Colchicine Site

R Álvarez, L Aramburu, P Puebla

  • 1Departamento de Química Farmacéutica, Facultad de Farmacia, Campus Miguel de Unamuno s/n, Universidad de Salamanca, Salamanca, 37007, Spain. pelaez@usal.es.

Current Medicinal Chemistry
|April 28, 2016
PubMed
Summary

Pyridines and azines are key scaffolds in developing novel antimitotic agents that target tubulin. This review explores pyridine and azine-containing colchicine site ligands (CSLs) for improved cancer and vascular disruption therapies.

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